KCNJ5 Antikörper (C-Term)

Produktnummer ABIN183662

Produktdetails anti-KCNJ5 Antikörper

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Bindungsspezifität: C-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNJ5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RSRSPGSYKQ RETRKRAQRN PGEEQSRRND SRSHGTDLYR GEKMYREHPG

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CIR. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CIR

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 450 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KCNJ5

Target: KCNJ5 (Potassium Inwardly-Rectifying Channel, Subfamily J, Member 5 (KCNJ5))

Andere Bezeichnung: CIR (KCNJ5 Produkte)

Synonyme: CIR antikoerper, GIRK4 antikoerper, KATP1 antikoerper, KIR3.4 antikoerper, LQT13 antikoerper, Kir3.4 antikoerper, GIRK-4 antikoerper, KATP-1 antikoerper, potassium voltage-gated channel subfamily J member 5 antikoerper, potassium inwardly-rectifying channel, subfamily J, member 5 antikoerper, KCNJ5 antikoerper, Kcnj5 antikoerper

Hintergrund: CIR may modulate splice site selection during alternative splicing of pre-mRNAs. CIR regulates transcription and acts as corepressor for RBPSUH by recruiting RBPSUH to the Sin3-histone deacetylase complex (HDAC). CIR is also required for RBPSUH-mediated repression of transcription.
Alias Symbols: CIR
Protein Interaction Partner: CEP76, NEK6, U2AF1, SRSF2, SRSF1, RP9, HDAC2, SAP30, SNW1, TCEA1, NCOR2, RBPJ,
Protein Size: 450

Molekulargewicht: 52 kDa

Gen-ID: 9541

NCBI Accession: NM_004882, NP_004873

UniProt: Q86X95

Pathways: Notch Signalweg