PTGES2 Antikörper (Middle Region)

Produktnummer ABIN2780102

Produktdetails anti-PTGES2 Antikörper

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PTGES2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: GAAAMYLISK RLKSRHHLQD DVRVDLYEAA NKWVTAVGKD RPFMGGQKPN

Homologie: Cow: 92%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 79%, Mouse: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Ptges2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Mouse Ptges2

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu PTGES2

Target: PTGES2 (Prostaglandin E Synthase 2 (PTGES2))

Andere Bezeichnung: Ptges2 (PTGES2 Produkte)

Synonyme: C9orf15 antikoerper, GBF-1 antikoerper, GBF1 antikoerper, PGES2 antikoerper, mPGES-2 antikoerper, Pges antikoerper, 2410099E23Rik antikoerper, D2Ertd369e antikoerper, mPGES antikoerper, mPGES-1 antikoerper, PTGES2 antikoerper, ptges2 antikoerper, zgc:56527 antikoerper, gbf1 antikoerper, pges2 antikoerper, 0610038H10Rik antikoerper, C79137 antikoerper, Gbf1 antikoerper, Mpges2 antikoerper, Pges2 antikoerper, MPGES-2 antikoerper, prostaglandin E synthase 2 antikoerper, prostaglandin E synthase antikoerper, prostaglandin E synthase 2-like antikoerper, PTGES2 antikoerper, Ptges antikoerper, Ptges2 antikoerper, ptgesl antikoerper, CpipJ_CPIJ003988 antikoerper, CpipJ_CPIJ018524 antikoerper, ptges2 antikoerper

Hintergrund: The protein encoded by this gene is a Golgi membrane-associated prostaglandin E synthase candidate, which is capable of catalyzing the conversion of prostaglandin H2 to prostaglandin E2 in vitro. However, a study using mice deficient of this gene suggests that this enzyme does not contribute to prostaglandin E2 biosynthesis in vivo. This protein is synthesized as a Golgi membrane-bound protein, but its N-terminal hydrophobic region is cleaved off during protein maturation to produce the predominant soluble truncated form that still retains the enzyme activity. This soluble protein also has been shown to activate the transcription regulated by a gamma-interferon-activated transcription element (GATE), possibly via an interaction with CAAAT/enhancer-binding protein-beta.
Alias Symbols: 0610038H10Rik, C79137, Gbf1, Mpges2, Pges2
Protein Size: 384

Molekulargewicht: 43 kDa

Gen-ID: 96979

NCBI Accession: NM_133783, NP_598544

UniProt: Q8BWM0

Pathways: Interferon-gamma Pathway, Cell RedoxHomeostasis, SARS-CoV-2 Protein Interaktom