TAF1A Antikörper (N-Term)

Produktnummer ABIN2780033

Produktdetails anti-TAF1A Antikörper

Target: TAF1A (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))

Bindungsspezifität: N-Term

Reaktivität: Ratte, Maus, Kaninchen, Pferd, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TAF1A Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: FAQTTSACLS FLQEALLKHQ WCRAAEYMHS YLQTLEDSDT YRKQAAPEII

Homologie: Guinea Pig: 86%, Horse: 91%, Mouse: 100%, Rabbit: 92%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against Taf1a. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N-terminal region of Rat Taf1a

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-TAF1A Antikörper (ABIN2780033)

Machida, Takeda, Yokono, Ikemune, Taniguchi, Kiyosawa, Takemasa: "Reduction of ribosome biogenesis with activation of the mTOR pathway in denervated atrophic muscle." in: Journal of cellular physiology, Vol. 227, Issue 4, pp. 1569-76, (2012) (PubMed).

Details zu TAF1A

Target: TAF1A (TATA Box Binding Protein (TBP)-Associated Factor, RNA Polymerase I, A, 48kDa (TAF1A))

Andere Bezeichnung: Taf1a (TAF1A Produkte)

Synonyme: TAFI48 antikoerper, mTAFI48 antikoerper, MGC:17061 antikoerper, RAFI48 antikoerper, SL1 antikoerper, TATA-box binding protein associated factor, RNA polymerase I, A antikoerper, TATA-box binding protein associated factor, RNA polymerase I subunit A antikoerper, Taf1a antikoerper, TAF1A antikoerper

Hintergrund: Taf1a is a component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1/TIF-IB with the rDNA promoter. SL1/TIF-IB is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA. Formation of SL1/TIF-IB excludes the association of TBP with TFIID subunits.
Alias Symbols: -
Protein Size: 453

Molekulargewicht: 49 kDa

Gen-ID: 360893

NCBI Accession: NM_001037204, NP_001032281

UniProt: Q3B7U2