AHRR Antikörper (Middle Region)

Produktnummer ABIN2779915

Produktdetails anti-AHRR Antikörper

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Bindungsspezifität: Middle Region

Reaktivität: Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser AHRR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: CLRGGPDLLD PKGTSGDREE EDQKHILRRS PGAWGQREMH KYSYGLETPV

Homologie: Mouse: 100%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against Ahrr. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide corresponding to a region of Mouse

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 701 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu AHRR

Target: AHRR (Aryl-Hydrocarbon Receptor Repressor (AHRR))

Andere Bezeichnung: Ahrr (AHRR Produkte)

Synonyme: mKIAA1234 antikoerper, AHH antikoerper, AHHR antikoerper, bHLHe77 antikoerper, ahh antikoerper, ahhr antikoerper, bhlhe77 antikoerper, ahrr2 antikoerper, aryl-hydrocarbon receptor repressor antikoerper, aryl hydrocarbon receptor repressor-like antikoerper, uncharacterized LOC723045 antikoerper, aryl-hydrocarbon receptor repressor L homeolog antikoerper, aryl hydrocarbon receptor repressor antikoerper, aryl-hydrocarbon receptor repressor b antikoerper, Ahrr antikoerper, AHRR antikoerper, LOC529500 antikoerper, LOC723045 antikoerper, ahrr.L antikoerper, LOC100455869 antikoerper, ahrr antikoerper, LOC100136487 antikoerper, ahrrb antikoerper

Hintergrund: Ahrr mediates dioxin toxicity and is involved in regulation of cell growth and differentiation. Ahrr represses the transcription activity of AHR by competing with this transcription factor for heterodimer formation with the ARNT and subsequently binding to the xenobiotic response element (XRE) sequence present in the promoter regulatory region of variety of genes. Ahrr represses CYP1A1 by binding the XRE sequence and recruiting ANKRA2, HDAC4 and/or HDAC5. Autoregulates its expression by associating with its own XRE site.
Alias Symbols: KIAA1234, mKIAA1234
Protein Size: 701

Molekulargewicht: 78 kDa

Gen-ID: 11624

NCBI Accession: NM_009644, NP_033774

UniProt: Q3U1U7

Pathways: Steroid Hormone Biosynthesis, Regulation of Lipid Metabolism by PPARalpha