CrkL Antikörper (Middle Region)
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- Target Alle CrkL (CRKL) Antikörper anzeigen
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CrkL Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- RSSPHGKHGN RNSNSYGIPE PAHAYAQPQT TTPLPAVSGS PGAAITPLPS
- Produktmerkmale
- This is a rabbit polyclonal antibody against CRKL. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of Human CRKL
- Top Product
- Discover our top product CRKL Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 303 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- CrkL (CRKL) (V-Crk Sarcoma Virus CT10 Oncogene Homolog (Avian)-Like (CRKL))
- Andere Bezeichnung
- CRKL (CRKL Produkte)
- Synonyme
- CRKL antikoerper, wu:fa55g05 antikoerper, wu:fj60e01 antikoerper, zgc:63469 antikoerper, 1110025F07Rik antikoerper, AA589403 antikoerper, AI325100 antikoerper, Crkol antikoerper, CRK like proto-oncogene, adaptor protein antikoerper, v-crk avian sarcoma virus CT10 oncogene homolog-like antikoerper, CRKL antikoerper, crkl antikoerper, Crkl antikoerper
- Hintergrund
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CRKL has been shown to activate the RAS and JUN kinase signaling pathways and transform fibroblasts in a RAS-dependent fashion. It is a substrate of the BCR-ABL tyrosine kinase and plays a role in fibroblast transformation by BCR-ABL. In addition, CRKL has oncogenic potential.
Alias Symbols: -
Protein Interaction Partner: HUWE1, UBC, BAG3, PIK3R2, DOK1, CBL, LMNA, SHANK3, GAREM, BIK, AOX1, WAC, POLR1D, TENC1, KHDRBS1, PPFIBP2, ARHGEF5, YY1, RPL31, ERBB3, ERBB2, PHC2, BCAR1, RAPGEF1, EPS15, EGFR, ABL1, STAT5A, PIK3R1, EPOR, ELAVL1, MSL1, PLEKHA1, LTBP4, PLSCR1, NOTCH2, LAMA
Protein Size: 303 - Molekulargewicht
- 34 kDa
- Gen-ID
- 1399
- NCBI Accession
- NM_005207, NP_005198
- UniProt
- P46109
- Pathways
- Interferon-gamma Pathway, Neurotrophin Signalübertragung, Signaling of Hepatocyte Growth Factor Receptor
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