ASH2L Antikörper (Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila)) (Middle Region)

Details for Product anti-ASH2L Antibody No. ABIN2778325, Anbieter: Anmelden zum Anzeigen
Antigen
  • ASH2
  • ASH2L1
  • ASH2L2
  • Bre2
  • fb34c06
  • fe38b04
  • fi20h02
  • wu:fb34c06
  • wu:fe38b04
  • wu:fi20h02
  • zgc:171444
  • ASH2L
  • ash2-like
  • ASH2 like histone lysine methyltransferase complex subunit
  • ash2 (absent, small, or homeotic)-like (Drosophila)
  • ash2 (absent, small, or homeotic)-like L homeolog
  • cataract, congenital, total
  • ASH2L
  • Ash2l
  • ash2l
  • ash2l.L
  • CCT
Epitop
Middle Region
22
7
5
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
Reaktivität
Rind (Kuh), Hund, Meerschweinchen, Pferd, Human, Maus, Kaninchen, Ratte (Rattus)
90
52
30
14
12
11
7
4
3
2
2
2
1
1
1
1
Wirt
Kaninchen
76
15
2
Klonalität
Polyklonal
Konjugat
Dieser ASH2L Antikörper ist unkonjugiert
3
3
3
1
1
1
1
1
1
1
1
1
1
1
1
Applikation
Immunohistochemistry (IHC), Western Blotting (WB)
81
43
29
23
15
12
9
8
5
3
2
2
1
1
1
Optionen
Hersteller
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Hersteller Produkt- Nr.
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Immunogen The immunogen is a synthetic peptide directed towards the middle region of human ASH2L
Blocking Peptide Zu diesem Produkt passt das Blocking Peptide ABIN973509.
Sequenz AAGSSGKGRG AKRKQQDGGT TGTTKKARSD PLFSAQRLPP HGYPLEHPFN
Homologie Cow: 86%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%
Produktmerkmale This is a rabbit polyclonal antibody against ASH2L. It was validated on Western Blot using a cell lysate as a positive control.
Reinigung Affinity Purified
Andere Bezeichnung ASH2L (ASH2L Antibody Abstract)
Hintergrund ASH2L is a component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. The protein may function as a transcriptional regulator and play a role in hematopoiesis.
Alias Symbols: ASH2, ASH2L1, ASH2L2, Bre2
Protein Interaction Partner: CXXC1, DPY30, SETD1A, RBBP5, PPARG, KMT2A, KMT2D, UBC, SENP3, KDM6A, PPP1CC, SMAD9, KDM6B, WWP1, BRCA1, BARD1, WDR5, MEN1, USF1, KMT2C, HCFC2, SETD1B, KDM4B, KMT2B, HCFC1, ESR1, CDC73, HIST3H3, PYGO2, WDR82, PSMC5, PRMT1, E2F4, E2F1, PAGR1, NCOA6, PAXIP1,
Protein Size: 628
Molekulargewicht 69 kDa
Gen-ID 9070
NCBI Accession NM_004674, NP_004665
UniProt Q9UBL3
Applikationshinweise Optimal working dilutions should be determined experimentally by the investigator.
Kommentare

Antigen size: 628 AA

Beschränkungen Nur für Forschungszwecke einsetzbar
Format Liquid
Konzentration Lot specific
Buffer Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
Konservierungsmittel Sodium azide
Vorsichtsmaßnahmen This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handhabung Avoid repeated freeze-thaw cycles.
Lagerung -20 °C
Informationen zur Lagerung For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Bilder des Herstellers
Western Blotting (WB) image for anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (Middle Region) antibody (ABIN2778325) WB Suggested Anti-ASH2L Antibody Titration: 0.2-1 ug/ml
ELISA Titer:
Immunohistochemistry (IHC) image for anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (Middle Region) antibody (ABIN2778325) anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (Middle Region) antibody (Image 2)
Immunohistochemistry (IHC) image for anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (Middle Region) antibody (ABIN2778325) anti-Ash2 (Absent, Small, Or Homeotic)-Like (Drosophila) (ASH2L) (Middle Region) antibody (Image 3)
Allgemeine Veröffentlichungen Lüscher-Firzlaff, Gawlista, Vervoorts, Kapelle, Braunschweig, Walsemann, Rodgarkia-Schamberger, Schuchlautz, Dreschers, Kremmer, Lilischkis, Cerni, Wellmann, Lüscher: "The human trithorax protein hASH2 functions as an oncoprotein." in: Cancer research, Vol. 68, Issue 3, pp. 749-58, 2008 (PubMed).

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