PPARA Antikörper (Middle Region)
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- Target Alle PPARA Antikörper anzeigen
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Schwein, Pferd, Ziege, Meerschweinchen, Kaninchen, Schaf
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser PPARA Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- IYEAYLKNFN MNKVKARVIL SGKASNNPPF VIHDMETLCM AEKTLVAKLV
- Homologie
- Dog: 92%, Goat: 91%, Guinea Pig: 77%, Horse: 92%, Human: 100%, Mouse: 85%, Pig: 92%, Rabbit: 85%, Rat: 85%, Sheep: 91%
- Produktmerkmale
- This is a rabbit polyclonal antibody against PPARA. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human PPARA
- Top Product
- Discover our top product PPARA Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 468 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- PPARA (Peroxisome Proliferator-Activated Receptor alpha (PPARA))
- Andere Bezeichnung
- PPARA (PPARA Produkte)
- Synonyme
- NR1C1 antikoerper, PPAR antikoerper, PPARalpha antikoerper, hPPAR antikoerper, LOC100136415 antikoerper, PPARALPHA antikoerper, nr1c1 antikoerper, xPPARalpha antikoerper, xppara antikoerper, 4933429D07Rik antikoerper, AW742785 antikoerper, Nr1c1 antikoerper, PPAR-alpha antikoerper, Ppar antikoerper, peroxisome proliferator activated receptor alpha antikoerper, peroxisome proliferator-activated receptor alpha antikoerper, peroxisome proliferator activated receptor alpha L homeolog antikoerper, PPARA antikoerper, LOC100136415 antikoerper, ppara.L antikoerper, Ppara antikoerper, ppara antikoerper
- Hintergrund
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Peroxisome proliferators include hypolipidemic drugs, herbicides, leukotriene antagonists, and plasticizers, this term arises because they induce an increase in the size and number of peroxisomes. Peroxisomes are subcellular organelles found in plants and animals which contain enzymes for respiration and for cholesterol and lipid metabolism. The action of peroxisome proliferators is thought to be mediated via specific receptors, called PPARs, which belong to the steroid hormone receptor superfamily. PPARs affect the expression of target genes involved in cell proliferation, cell differentiation and in immune and inflammation responses. Three closely related subtypes (alpha, beta/delta, and gamma) have been identified. This gene encodes the subtype PPAR-alpha, which is a nuclear transcription factor.
Alias Symbols: PPAR, NR1C1, hPPAR, PPARalpha
Protein Interaction Partner: SIRT1, PRMT1, PRMT8, RXRA, CHD9, NCOA1, FOXA3, CDK3, TNP1, HSP90AA1, NCOR2, NCOR1, SUMO1, UBE2I, LPIN1, SRC, TRA, MECR, STAC3, HELZ2, NRBF2, AIP, NR1H3, MED24, GADD45G, GADD45B, AKAP13, PPARGC1A, MED1, EP300, NRIP1, DAP3, MAPK3, DUT, RXRG, PRKCD, PRKCA, M
Protein Size: 468 - Molekulargewicht
- 51 kDa
- Gen-ID
- 5465
- NCBI Accession
- NM_005036, NP_005027
- UniProt
- Q07869
- Pathways
- Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway, Regulation of Lipid Metabolism by PPARalpha, Regulation of Carbohydrate Metabolic Process, Hepatitis C
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