POU4F3 Antikörper (Middle Region)

Produktnummer ABIN182736

Produktdetails anti-POU4F3 Antikörper

Target: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Zebrafisch (Danio rerio), Meerschweinchen, Pferd, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser POU4F3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: ALANLKIPGV GSLSQSTICR FESLTLSHNN MIALKPVLQA WLEEAEAAYR

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against POU4F3. It was validated on Western Blot and immunohistochemistry.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human POU4F3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 338 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu POU4F3

Target: POU4F3 (POU Domain, Class 4, Transcription Factor 3 (POU4F3))

Andere Bezeichnung: POU4F3 (POU4F3 Produkte)

Synonyme: POU4F3 antikoerper, BRN-3 antikoerper, BRN3 antikoerper, BRN3C antikoerper, DFNA15 antikoerper, BRN-3.1 antikoerper, brn-3c antikoerper, brn3.1 antikoerper, brn3c antikoerper, Brn3.1 antikoerper, Brn3c antikoerper, ddl antikoerper, dreidel antikoerper, POU class 4 homeobox 3 antikoerper, POU domain, class 4, transcription factor 3 antikoerper, POU4F3 antikoerper, Pou4f3 antikoerper, pou4f3 antikoerper

Hintergrund: POU4F3 is capable of activating both BDNF and NT-3 promoters in inner ear sensory epithelial cell lines. Mutant POU4F3 loses most of its transcriptional activity and most of its ability to bind to DNA. The mutation causes autosomal-dominant nonsyndromic hearing loss and eventually leads to hair cell morbidity in affected family members.
Alias Symbols: BRN3C, DFNA15
Protein Size: 338

Molekulargewicht: 37 kDa

Gen-ID: 5459

NCBI Accession: NM_002700, NP_002691

UniProt: Q15319

Pathways: Sensory Perception of Sound