JDP2 Antikörper (N-Term)

Produktnummer ABIN2777349

Produktdetails anti-JDP2 Antikörper

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Bindungsspezifität: N-Term

Reaktivität: Human, Ratte, Maus, Hund, Pferd, Rind (Kuh), Meerschweinchen, Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JDP2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: LPGLGPLTGL PSSALTVEEL KYADIRNLGA MIAPLHFLEV KLGKRPQPVK

Homologie: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 93%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against JDP2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 163 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu JDP2

Target: JDP2 (Jun Dimerization Protein 2 (JDP2))

Andere Bezeichnung: JDP2 (JDP2 Produkte)

Synonyme: JUNDM2 antikoerper, JDP2 antikoerper, Jundm2 antikoerper, Jundp2 antikoerper, TIF antikoerper, fk87c02 antikoerper, wu:fk87c02 antikoerper, zgc:92851 antikoerper, Jun dimerization protein 2 antikoerper, Jun dimerization protein 2b antikoerper, JDP2 antikoerper, Jdp2 antikoerper, jdp2b antikoerper

Hintergrund: JDP2 is a component of the AP-1 transcription factor that represses transactivation mediated by the Jun family of proteins. It is involved in a variety of transcriptional responses associated with AP-1 such as UV-induced apoptosis, cell differentiation, tumorigenesis and antitumogeneris. It can also function as a repressor by recruiting histone deacetylase 3/HDAC3 to the promoter region of JUN. It may control transcription via direct regulation of the modification of histones and the assembly of chromatin.
Alias Symbols: JUNDM2
Protein Interaction Partner: HDAC10, HDAC5, HDAC6, HDAC4, HDAC1, ELAVL1, PGR, JDP2, ATF2, GTF2H1, KAT2B, SNW1, MAPK9, EP300, MAPK8, MAPK14, CREBBP, JUND, JUNB, JUN, IRF2BP1, ATF7, UBC,
Protein Size: 163

Molekulargewicht: 19 kDa

Gen-ID: 122953

NCBI Accession: NM_130469, NP_569736

UniProt: Q8WYK2

Pathways: Chromatin Binding