SERPINB5 Antikörper (Middle Region)
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- Target Alle SERPINB5 Antikörper anzeigen
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
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Bindungsspezifität
- Middle Region
- Reaktivität
- Human, Maus, Ratte, Kaninchen, Rind (Kuh), Meerschweinchen, Hund, Pferd
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser SERPINB5 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (IHC)
- Sequenz
- NSVNDQTKIL VVNAAYFVGK WMKKFPESET KECPFRLNKT DTKPVQMMNM
- Homologie
- Cow: 86%, Dog: 93%, Guinea Pig: 86%, Horse: 93%, Human: 93%, Mouse: 86%, Rabbit: 86%, Rat: 93%
- Produktmerkmale
- This is a rabbit polyclonal antibody against SERPINB5. It was validated on Western Blot and immunohistochemistry.
- Aufreinigung
- Protein A purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SERPINB5
- Top Product
- Discover our top product SERPINB5 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 375 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." in: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).
: "Cancer cell resistance to aurora kinase inhibitors: identification of novel targets for cancer therapy." in: Journal of proteome research, Vol. 12, Issue 1, pp. 455-69, (2013) (PubMed).
: "SERPINB5 and AKAP12 - expression and promoter methylation of metastasis suppressor genes in pancreatic ductal adenocarcinoma." in: BMC cancer, Vol. 10, pp. 549, (2010) (PubMed).
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SERPINB5 Promoter Hypomethylation Differentiates Pancreatic Ductal Adenocarcinoma From Pancreatitis." in: Pancreas, Vol. 45, Issue 5, pp. 743-7, (2016) (PubMed).
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- Target
- SERPINB5 (serpin Peptidase Inhibitor, Clade B (Ovalbumin), Member 5 (SERPINB5))
- Andere Bezeichnung
- SERPINB5 (SERPINB5 Produkte)
- Synonyme
- 1110036M19Rik antikoerper, AI462524 antikoerper, AI646751 antikoerper, Maspin antikoerper, PI-5 antikoerper, Spi7 antikoerper, ovalbumin antikoerper, PI5 antikoerper, maspin antikoerper, Pi5 antikoerper, serine (or cysteine) peptidase inhibitor, clade B, member 5 antikoerper, serpin family B member 5 antikoerper, serpin peptidase inhibitor, clade B (ovalbumin), member 5 S homeolog antikoerper, Serpinb5 antikoerper, SERPINB5 antikoerper, serpinb5.S antikoerper
- Hintergrund
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As a tumor suppressor, it blocks the growth, invasion, and metastatic properties of mammary tumors. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.
Alias Symbols: PI5, maspin
Protein Interaction Partner: SUMO2, WWOX, FBXO32, KHDRBS3, ISG15, UBC, Cdk1, UCHL5, HDAC1,
Protein Size: 375 - Molekulargewicht
- 41 kDa
- Gen-ID
- 5268
- NCBI Accession
- NM_002639, NP_002630
- UniProt
- P36952
- Pathways
- p53 Signalweg
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