TNNI3 Antikörper (Middle Region)

Produktnummer ABIN2776782

Produktdetails anti-TNNI3 Antikörper

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Bindungsspezifität: Middle Region

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Kaninchen, Ziege, Pferd, Meerschweinchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TNNI3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Sequenz: RVRISADAMM QALLGARAKE SLDLRAHLKQ VKKEDTEKEN REVGDWRKNI

Homologie: Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against TNNI3. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human TNNI3

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 210 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu TNNI3

Target: TNNI3 (Cardiac Troponin I (TNNI3))

Andere Bezeichnung: TNNI3 (TNNI3 Produkte)

Synonyme: CMD1FF antikoerper, CMD2A antikoerper, CMH7 antikoerper, RCM1 antikoerper, TNNC1 antikoerper, cTnI antikoerper, CMD1Z antikoerper, CMH13 antikoerper, TN-C antikoerper, TNC antikoerper, TNNC antikoerper, Tn1 antikoerper, TnIc antikoerper, ctnIc antikoerper, XTnIc antikoerper, c-troponin antikoerper, cTNT antikoerper, cmh7 antikoerper, ctni antikoerper, tnnc1 antikoerper, TNNI3 antikoerper, TnI antikoerper, cTNI antikoerper, AI874626 antikoerper, TnC antikoerper, cTnC antikoerper, tncc antikoerper, Tncc antikoerper, troponin I3, cardiac type antikoerper, troponin C1, slow skeletal and cardiac type antikoerper, troponin I, cardiac 3 antikoerper, troponin I type 3 (cardiac) antikoerper, troponin I3, cardiac type S homeolog antikoerper, troponin I3, cardiac type L homeolog antikoerper, cardiac troponin I antikoerper, troponin C, cardiac/slow skeletal antikoerper, TNNI3 antikoerper, TNNC1 antikoerper, Tnni3 antikoerper, tnni3.S antikoerper, tnni3.L antikoerper, tnni3 antikoerper, LOC100462680 antikoerper, Tnnc1 antikoerper

Hintergrund: Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. TNNI3 is the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues.Troponin I (TnI), along with troponin T (TnT) and troponin C (TnC), is one of 3 subunits that form the troponin complex of the thin filaments of striated muscle. TnI is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. The TnI subfamily contains three genes: TnI-skeletal-fast-twitch, TnI-skeletal-slow-twitch, and TnI-cardiac. This gene encodes the TnI-cardiac protein and is exclusively expressed in cardiac muscle tissues. Mutations in this gene cause familial hypertrophic cardiomyopathy type 7 (CMH7) and familial restrictive cardiomyopathy (RCM). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: CMH7, MGC116817, TNNC1, cTnI, RCM1, CMD2A, CMD1FF
Protein Interaction Partner: TNNC2, TRIM63, TRIM55, RCAN3, TNNC1, TNNI3K, PKD2L1, TNNI3, TNNT2, TNNT1, PRKCA, PAPPA, PKD2, ACTA1, LYST,
Protein Size: 210

Molekulargewicht: 23 kDa

Gen-ID: 7137

NCBI Accession: NM_000363, NP_000354

UniProt: Q59H18