KCNQ1 Antikörper (N-Term)

Produktnummer ABIN2776340

Produktdetails anti-KCNQ1 Antikörper

Target: KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Zebrafisch (Danio rerio)

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCNQ1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: IVVVASMVVL CVGSKGQVFA TSAIRGIRFL QILRMLHVDR QGGTWRLLGS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against KCNQ1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human KCNQ1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 549 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu KCNQ1

Target: KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))

Andere Bezeichnung: KCNQ1 (KCNQ1 Produkte)

Synonyme: ATFB1 antikoerper, ATFB3 antikoerper, JLNS1 antikoerper, KCNA8 antikoerper, KCNA9 antikoerper, KVLQT1 antikoerper, Kv1.9 antikoerper, Kv7.1 antikoerper, LQT antikoerper, LQT1 antikoerper, RWS antikoerper, SQT2 antikoerper, WRS antikoerper, CG12215 antikoerper, CG12915 antikoerper, CG33135 antikoerper, DKCNQ antikoerper, Dmel\\CG33135 antikoerper, dKCNQ antikoerper, kcnq1 antikoerper, KCNQ1 antikoerper, kqt-3 antikoerper, kv7.1 antikoerper, Kvlqt1 antikoerper, KvLQT-1 antikoerper, kcnq1-A antikoerper, xkvlqt1 antikoerper, zgc:158384 antikoerper, AW559127 antikoerper, Kcna9 antikoerper, KvLQT1 antikoerper, potassium voltage-gated channel subfamily Q member 1 antikoerper, KCNQ potassium channel antikoerper, potassium voltage-gated channel, KQT-like subfamily, member 1 antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 1 antikoerper, voltage gated potassium channel subunit antikoerper, potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog antikoerper, potassium voltage-gated channel, subfamily Q, member 1 antikoerper, KCNQ1 antikoerper, KCNQ antikoerper, kcnq1 antikoerper, Kcnq1 antikoerper, kcnq1.L antikoerper

Hintergrund: KCNQ1 encodes a protein for a voltage-gated potassium channel required for the repolarization phase of the cardiac action potential. The gene product can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in KCNQ1 are associated with hereditary long QT syndrome, Romano-Ward syndrome, Jervell and Lange-Nielsen syndrome and familial atrial fibrillation.
Alias Symbols: LQT, RWS, WRS, LQT1, SQT2, ATFB1, ATFB3, JLNS1, KCNA8, KCNA9, Kv1.9, Kv7.1, KVLQT1
Protein Interaction Partner: ATP4A, NEDD4L, AP2M1, USP2, UBC, NEDD4, PRKACA, KCNE1, HSPA4, KCNE4, AKAP9, KCNE2, TRAF6, KCNQ2, PRKAR2A, PPP1CA,
Protein Size: 549

Molekulargewicht: 60 kDa

Gen-ID: 3784

NCBI Accession: NM_181798, NP_861463

Pathways: Negative Regulation of Hormone Secretion, Sensory Perception of Sound