P2RX4 Antikörper (N-Term)

Produktnummer ABIN2776331

Produktdetails anti-P2RX4 Antikörper

Target: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Bindungsspezifität: N-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein, Meerschweinchen, Zebrafisch (Danio rerio), Kaninchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser P2RX4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: VQLLILAYVI GWVFVWEKGY QETDSVVSSV TTKVKGVAVT NTSKLGFRIW

Homologie: Cow: 86%, Dog: 93%, Guinea Pig: 86%, Human: 100%, Mouse: 93%, Pig: 93%, Rabbit: 93%, Rat: 93%, Zebrafish: 86%

Produktmerkmale: This is a rabbit polyclonal antibody against P2RX4. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human P2RX4

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 388 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu P2RX4

Target: P2RX4 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 4 (P2RX4))

Andere Bezeichnung: P2RX4 (P2RX4 Produkte)

Synonyme: P2X4 antikoerper, P2X4R antikoerper, AI504491 antikoerper, AW555605 antikoerper, D5Ertd444e antikoerper, p2rx4 antikoerper, p2x4 antikoerper, wu:fi03f02 antikoerper, p2x4r antikoerper, p2rx4.2 antikoerper, p2xr4.2 antikoerper, purinergic receptor P2X 4 antikoerper, purinergic receptor P2X, ligand-gated ion channel 4 antikoerper, purinergic receptor P2X, ligand-gated ion channel, 4a antikoerper, purinergic receptor P2X, ligand gated ion channel, 4 L homeolog antikoerper, purinergic receptor P2X, ligand-gated ion channel, 4b antikoerper, P2RX4 antikoerper, P2rx4 antikoerper, p2rx4a antikoerper, p2rx4.L antikoerper, p2rx4b antikoerper

Hintergrund: P2RX4 is the receptor for ATP that acts as a ligand gated ion channel. This receptor is insensitive to the antagonists PPADS and suramin.The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel with high calcium permeability. The main pharmacological distinction between the members of the purinoceptor family is the relative sensitivity to the antagonists suramin and PPADS. The product of this gene has the lowest sensitivity for these antagonists. Multiple alternatively spliced transcript variants have been identified for this gene although their full-length natures have not been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: P2X4, P2X4R
Protein Interaction Partner: NOTCH2NL, PIH1D3, KRTAP5-9, WNT4, MCM2, CDH5,
Protein Size: 388

Molekulargewicht: 43 kDa

Gen-ID: 5025

NCBI Accession: NM_002560, NP_002551

UniProt: Q99571

Pathways: Synaptic Membrane