CLCN6 Antikörper (C-Term)

Produktnummer ABIN2776242

Produktdetails anti-CLCN6 Antikörper

Target: CLCN6 (Chloride Channel, Voltage-Sensitive 6 (CLCN6))

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Kaninchen, Hund, Rind (Kuh), Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLCN6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: PQFQSISLRK IQFNFPYFRS DRDKRDFVSA GAAAGVAAAF GAPIGGTLFS

Homologie: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against CLCN6. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CLCN6

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 353 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-CLCN6 Antikörper (ABIN2776242)

Jensen, Nosjean, Dziegiel, Boutin, Sørensen, Karsdal, Henriksen: "A quantitative assay for lysosomal acidification rates in human osteoclasts." in: Assay and drug development technologies, Vol. 9, Issue 2, pp. 157-64, (2011) (PubMed).

Tran, Leclerc, Chan, Pai, Hiou-Tim, Wu, Goyette, Artigas, Milos, Rozen: "Multiple transcription start sites and alternative splicing in the methylenetetrahydrofolate reductase gene result in two enzyme isoforms." in: Mammalian genome : official journal of the International Mammalian Genome Society, Vol. 13, Issue 9, pp. 483-92, (2002) (PubMed).

Details zu CLCN6

Target: CLCN6 (Chloride Channel, Voltage-Sensitive 6 (CLCN6))

Andere Bezeichnung: CLCN6 (CLCN6 Produkte)

Synonyme: CLC-6 antikoerper, AI850629 antikoerper, CLCN6 antikoerper, wu:fb95f01 antikoerper, DKFZp469B244 antikoerper, DKFZp469L0417 antikoerper, chloride voltage-gated channel 6 antikoerper, chloride channel, voltage-sensitive 6 antikoerper, chloride channel 6 antikoerper, chloride transport protein 6 antikoerper, CLCN6 antikoerper, Clcn6 antikoerper, clcn6 antikoerper, LOC579870 antikoerper

Hintergrund: The CLCN family of voltage-dependent chloride channel genes comprises nine members (CLCN1-7, Ka and Kb) which demonstrate quite diverse functional characteristics while sharing significant sequence homology. Chloride channel 6 and 7 belong to a subbranch of this family. Chloride channel 6 has four different alternatively spliced transcript variants. This gene is in close vicinity to two other kidney-specific chloride channel genes, CLCNKA and CLCNKB.
Alias Symbols: CLC-6
Protein Interaction Partner: UBC, PPP2R1A,
Protein Size: 353

Molekulargewicht: 39 kDa

Gen-ID: 1185

NCBI Accession: NM_021736, NP_068504

UniProt: Q5SNX3