P2RX7 Antikörper (Middle Region)
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- Target Alle P2RX7 Antikörper anzeigen
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
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Bindungsspezifität
- Middle Region
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Reaktivität
- Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen, Schwein
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser P2RX7 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB)
- Sequenz
- LRHCAYRCYA TWRFGSQDMA DFANLPSCCR WRIRKEFPKS EGQYSGFKSP
- Homologie
- Cow: 100%, Dog: 93%, Guinea Pig: 83%, Horse: 86%, Human: 100%, Mouse: 92%, Pig: 93%, Rabbit: 93%, Rat: 85%
- Produktmerkmale
- This is a rabbit polyclonal antibody against P2RX7. It was validated on Western Blot using a cell lysate as a positive control.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human P2RX7
- Top Product
- Discover our top product P2RX7 Primärantikörper
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- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
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Antigen size: 595 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- P2RX7 (Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
- Andere Bezeichnung
- P2RX7 (P2RX7 Produkte)
- Synonyme
- p2xr7 antikoerper, P2RX7 antikoerper, P2X7 antikoerper, AI467586 antikoerper, P2X(7) antikoerper, P2X7R antikoerper, p2x7 antikoerper, purinergic receptor P2X 7 antikoerper, purinergic receptor P2X, ligand-gated ion channel, 7 antikoerper, P2X purinoceptor 7 antikoerper, P2RX7 antikoerper, p2rx7 antikoerper, LOC100458463 antikoerper, P2rx7 antikoerper
- Hintergrund
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The product P2RX7 belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants which would encode different isoforms have been identified although some fit nonsense-mediated decay (NMD) criteria. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
Alias Symbols: MGC20089, P2X7
Protein Interaction Partner: KRTAP10-8, KRT31, TM9SF1, CASK, EFNB3, EMP3, PANX1, SVIL, ACTB,
Protein Size: 595 - Molekulargewicht
- 68 kDa
- Gen-ID
- 5027
- NCBI Accession
- NM_002562, NP_002553
- UniProt
- Q99572
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Synaptic Vesicle Exocytosis
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