IGLL1 Antikörper (N-Term)

Produktnummer ABIN2775471

Produktdetails anti-IGLL1 Antikörper

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Bindungsspezifität: N-Term

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IGLL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: RSRWGRFLLQ RGSWTGPRCW PRGFQSKHNS VTHVFGSGTQ LTVLSQPKAT

Homologie: Human: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against IGLL1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Protein A purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human IGLL1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 213 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu IGLL1

Target: IGLL1 (Immunoglobulin lambda-Like Polypeptide 1 (IGLL1))

Andere Bezeichnung: IGLL1 (IGLL1 Produkte)

Synonyme: 14.1 antikoerper, AGM2 antikoerper, CD179b antikoerper, IGL1 antikoerper, IGL5 antikoerper, IGLJ14.1 antikoerper, IGLL antikoerper, IGO antikoerper, IGVPB antikoerper, VPREB2 antikoerper, IGLV antikoerper, IGLL1 antikoerper, MGC151892 antikoerper, Igll1 antikoerper, BB139905 antikoerper, Igl-5 antikoerper, Igll antikoerper, Lambda5 antikoerper, immunoglobulin lambda like polypeptide 1 antikoerper, immunoglobulin lambda-like polypeptide 1 antikoerper, IGLL1 antikoerper, Igll1 antikoerper

Hintergrund: The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. IGLL1 is one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. Mutations in its gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made.The preB cell receptor is found on the surface of proB and preB cells, where it is involved in transduction of signals for cellular proliferation, differentiation from the proB cell to the preB cell stage, allelic exclusion at the Ig heavy chain gene locus, and promotion of Ig light chain gene rearrangements. The preB cell receptor is composed of a membrane-bound Ig mu heavy chain in association with a heterodimeric surrogate light chain. This gene encodes one of the surrogate light chain subunits and is a member of the immunoglobulin gene superfamily. This gene does not undergo rearrangement. Mutations in this gene can result in B cell deficiency and agammaglobulinemia, an autosomal recessive disease in which few or no gamma globulins or antibodies are made. Two transcript variants encoding different isoforms have been found for this gene.
Alias Symbols: 14.1, CD179b, IGL1, IGL5, IGLJ14.1, IGLL, IGO, IGVPB, VPREB2, AGM2
Protein Interaction Partner: MYOC, IGLL1,
Protein Size: 213

Molekulargewicht: 19 kDa

Gen-ID: 3543

NCBI Accession: NM_020070, NP_064455

UniProt: P15814

Pathways: Regulation of Cell Size