KIR2DL5A Antikörper (C-Term)
-
- Target Alle KIR2DL5A Antikörper anzeigen
- KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))
-
Bindungsspezifität
- C-Term
-
Reaktivität
- Human
-
Wirt
- Kaninchen
-
Klonalität
- Polyklonal
-
Konjugat
- Dieser KIR2DL5A Antikörper ist unkonjugiert
-
Applikation
- Western Blotting (WB)
- Sequenz
- QLDHCVFTQT KITSPSQRPK TPPTDTTMYM ELPNAKPRSL SPAHKHHSQA
- Homologie
- Human: 100%
- Produktmerkmale
- This is a rabbit polyclonal antibody against KIR2DL5A. It was validated on Western Blot.
- Aufreinigung
- Affinity Purified
- Immunogen
- The immunogen is a synthetic peptide directed towards the C-terminal region of Human KIR2DL5A
- Top Product
- Discover our top product KIR2DL5A Primärantikörper
-
-
- Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
- Kommentare
-
Antigen size: 375 AA
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
-
- Format
- Liquid
- Konzentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handhabung
- Avoid repeated freeze-thaw cycles.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
-
- Target
- KIR2DL5A (Killer Cell Immunoglobulin-Like Receptor, Two Domains, Long Cytoplasmic Tail, 5A (KIR2DL5A))
- Andere Bezeichnung
- KIR2DL5A (KIR2DL5A Produkte)
- Synonyme
- CD158F antikoerper, KIR2DL5 antikoerper, KIR2DL5.1 antikoerper, KIR2DL5.3 antikoerper, KIR2DL5B antikoerper, killer cell immunoglobulin like receptor, two Ig domains and long cytoplasmic tail 5A antikoerper, KIR2DL5A antikoerper
- Hintergrund
-
Killer cell immunoglobulin-like receptors (KIRs) are transmembrane glycoproteins expressed by natural killer cells and subsets of T cells. The KIR genes are polymorphic and highly homologous and they are found in a cluster on chromosome 19q13.4 within the 1 Mb leukocyte receptor complex (LRC). The gene content of the KIR gene cluster varies among haplotypes, although several "framework" genes are found in all haplotypes (KIR3DL3, KIR3DP1, KIR3DL4, KIR3DL2). The KIR proteins are classified by the number of extracellular immunoglobulin domains (2D or 3D) and by whether they have a long (L) or short (S) cytoplasmic domain. KIR proteins with the long cytoplasmic domain transduce inhibitory signals upon ligand binding via an immune tyrosine-based inhibitory motif (ITIM), while KIR proteins with the short cytoplasmic domain lack the ITIM motif and instead associate with the TYRO protein tyrosine kinase binding protein to transduce activating signals. The ligands for several KIR proteins are subsets of HLA class I molecules, thus, KIR proteins are thought to play an important role in regulation of the immune response.
Alias Symbols: CD158F, KIR2DL5, KIR2DL5.1, KIR2DL5.3
Protein Interaction Partner: PTPN6, PTPN11,
Protein Size: 375 - Molekulargewicht
- 41 kDa
- Gen-ID
- 57292
- NCBI Accession
- NM_020535, NP_065396
- UniProt
- Q8N109
-