UACA Antikörper (C-Term)

Produktnummer ABIN2774333

Produktdetails anti-UACA Antikörper

Target: UACA

Bindungsspezifität: C-Term

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Kaninchen, Hund, Meerschweinchen, Pferd

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UACA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Sequenz: TELLNDVERL KQALNGLSQL TYTSGNPTKR QSQLIDTLQH QVKSLEQQLA

Homologie: Cow: 100%, Dog: 85%, Guinea Pig: 86%, Horse: 86%, Human: 100%, Mouse: 85%, Rabbit: 92%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against UACA. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 1403 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UACA

Target: UACA

Andere Bezeichnung: UACA (UACA Produkte)

Synonyme: NUCLING antikoerper, 2700059D02Rik antikoerper, nucling antikoerper, RGD1560011 antikoerper, uveal autoantigen with coiled-coil domains and ankyrin repeats antikoerper, UACA antikoerper, Uaca antikoerper

Hintergrund: UACA regulates APAF1 expression and plays an important role in the regulation of stress-induced apoptosis. It promotes apoptosis by regulating three pathways, apoptosome up-regulation, LGALS3/galectin-3 down-regulation and NF-kappa-B inactivation. It regulates the redistribution of APAF1 into the nucleus after proapoptotic stress and down-regulates the expression of LGALS3 by inhibiting NFKB1.
Alias Symbols: FLJ10128, KIAA1561, MGC141967, MGC141969, NUCLING
Protein Interaction Partner: KRT40, FUS, RNF2, HIF1AN, PAN2, TP63, UBC, USP48, RABEP1, STAMBP, FBXO25, NRD1, Mprip, MED14, CELSR3,
Protein Size: 1403

Molekulargewicht: 154 kDa

Gen-ID: 55075

NCBI Accession: NM_001008224, NP_001008225

UniProt: Q9BZF9

Pathways: Positive Regulation of Endopeptidase Activity