PPAP2B Antikörper

Produktnummer ABIN2764066

Produktdetails anti-PPAP2B Antikörper

Target: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PPAP2B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Kreuzreaktivität: Human, Maus, Ratte

Produktmerkmale: PAP2B,Vascular endothelial growth factor and type I collagen inducible protein (VCIP), also known as phosphatidic acid phosphatase 2b (PAP2b), was originally identified in a functional assay of angiogenesis. VCIP/PAP2b exhibits an ArgGlyAsp (RGD) cell adhesion sequence. Immunoprecipitation and fluorescence-activated cell sorting analyses demonstrated that VCIP-RGD is exposed to the outside of the cell surface. Retroviral transduction of VCIP can induce cell aggregation and cell cell interactions, modestly increase p120 catenin expression and promote activation of the Fak, Akt and GSK3 protein kinases. Expression of VCIP promoted adhesion, spreading and tyrosine phosphorylation of Fak, Shc, Cas and paxillin in endothelial cells. PAP2b/VCIP is expressed in close proximity to vascular endothelial growth factor, von Willebrand factor and {alpha}v3 integrin in tumor vasculatures.

Aufreinigung: Antigen Immunoaffiinity Purification

Immunogen: Synthetic peptide derived from the phosphatidic acid phosphatase 2B protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Antibody can be used for Western blotting (see vial for dilution) and EIA. Optimal concentration should be evaluated by serial dilutions.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: Lot specific

Buffer: Provided as solution in phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Product should be stored at -20°C. Aliquot to avoid freeze/thaw cycles

Details zu PPAP2B

Target: PPAP2B (Phosphatidic Acid Phosphatase Type 2B (PPAP2B))

Andere Bezeichnung: Phosphatidic Acid Phosphatase 2B (PPAP2B Produkte)

Synonyme: Dri42 antikoerper, LPP3 antikoerper, PAP2B antikoerper, VCIP antikoerper, 1110003O22Rik antikoerper, 2610002D05Rik antikoerper, AV025606 antikoerper, D4Bwg0538e antikoerper, D4Bwg1535e antikoerper, Lpp3 antikoerper, Ppab2b antikoerper, dri42 antikoerper, lpp3 antikoerper, pap2b antikoerper, ppap2bb antikoerper, vcip antikoerper, ppap2b antikoerper, ppap2ba antikoerper, PPAP2B antikoerper, si:dkey-19f4.1 antikoerper, phospholipid phosphatase 3 antikoerper, phospholipid phosphatase 3 L homeolog antikoerper, phospholipid phosphatase 3 S homeolog antikoerper, PLPP3 antikoerper, Plpp3 antikoerper, plpp3.L antikoerper, plpp3.S antikoerper, plpp3 antikoerper

UniProt: O14495