CD20 Antikörper

Produktnummer ABIN2739107

Produktdetails anti-CD20 Antikörper

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD20 Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunofluorescence (IF), ELISA, Immunoprecipitation (IP), Immunohistochemistry (Frozen Sections) (IHC (fro))

Spezifität: Human CD20

Aufreinigung: Protein G purified

Immunogen: The lymphoblastoid cell line Daudi.

Type of Immunogen: Cells

Klon: B9E9

Isotyp: IgG2a kappa

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo (0.5 - 1 μg/10 x10⁶), IF (0.5 - 1 μg/mL), IHC, IHC-Fr (0.5 - 1 μg/mL), IP

Usage: This antibody recognizes a protein of 33-37  kDa, identified as CD20 (Workshop V. Code CD20.12). The antibody recognizes the extracellular domain of CD20. The epitope is similar to or identical to that recognized by other CD20 antibodies including Leu-16 and B1. This antibody can be used for immunophenotyping of leukemia and malignant cells, B lymphocyte detection in peripheral blood, Bcell localization in tissues and B lymphocyte purification by immunosorbent methods. CD20 is a non-Ig differentiation antigen of Bcells and its expression is restricted to normal and neoplastic Bcells, being absent from all other leukocytes and tissues. It is expressed by pre Bcells and persists during all stages of Bcell maturation but is lost upon terminal differentiation into plasma cells. Protein passes through the membrane 4 times with both ends in cytoplasm and exposes one short and one longer loop to the external environment. CD20 is not glycosylated in resting Bcells and its cytoplasmic domains are differentially phosphorylated upon activation. It acts as a calcium channel involved in Bcell activation and cell cycle progression. ELISA: Order BSA-free antibody format for coating.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS,  pH 7.4, 0.1 mg/mL BSA, 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 2°C to 8°C.

Details zu CD20

Target: CD20 (MS4A1) (Membrane-Spanning 4-Domains, Subfamily A, Member 1 (MS4A1))

Andere Bezeichnung: CD20 (MS4A1 Produkte)

Synonyme: B1 antikoerper, Bp35 antikoerper, CD20 antikoerper, CVID5 antikoerper, LEU-16 antikoerper, MS4A2 antikoerper, S7 antikoerper, AA960661 antikoerper, Cd20 antikoerper, Ly-44 antikoerper, Ms4a2 antikoerper, MS4A1 antikoerper, bp35 antikoerper, cd20 antikoerper, ms4a2 antikoerper, leu-16 antikoerper, ms4a4c antikoerper, cd20-like antikoerper, membrane spanning 4-domains A1 antikoerper, membrane-spanning 4-domains, subfamily A, member 1 antikoerper, B-lymphocyte antigen CD20 antikoerper, MS4A1 antikoerper, Ms4a1 antikoerper, ms4a1 antikoerper, LOC101694281 antikoerper

Hintergrund: Name/Gene ID: MS4A1

Synonyms: MS4A1, B-lymphocyte antigen CD20, B1, Bp35, CD20, CD20 antigen, CD20 receptor, LEU-16, CVID5

Gen-ID: 931