CCM2 Antikörper
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- Target Alle CCM2 Antikörper anzeigen
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CCM2 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunofluorescence (IF)
- Produktmerkmale
- Homo sapiens cerebral cavernous malformation 2 (CCM2), transcript variant 2
- Aufreinigung
- Purified from mouse ascites fluids by affinity chromatography
- Immunogen
- Full length human recombinant protein of human CCM2(NP_113631) produced in HEK293T cell.
- Klon
- 5H4
- Isotyp
- IgG2b
- Top Product
- Discover our top product CCM2 Primärantikörper
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anti-Cerebral Cavernous Malformation 2 (CCM2) (Internal Region) antibody
Verified CCM2 Reaktivität: Human, Ratte WB, IF, ELISA, FACS Wirt: Ziege Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) antibodyCCM2 Reaktivität: Human, Maus, Ratte IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 Reaktivität: Human WB Wirt: Maus Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-300) antibodyCCM2 Reaktivität: Human IHC, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 2-100) antibodyCCM2 Reaktivität: Human WB, ELISA Wirt: Maus Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444) antibodyCCM2 Reaktivität: Human WB Wirt: Kaninchen Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) antibodyCCM2 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Cerebral Cavernous Malformation 2 (CCM2) (AA 1-444), (N-Term) antibodyCCM2 Reaktivität: Human WB, IF Wirt: Kaninchen Polyclonal unconjugated
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- Applikationshinweise
- WB 1:2000, IF 1:100,
- Kommentare
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The concentration of the product may vary between diferrent lots.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 0.5-1.0 mg/mL
- Buffer
- PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
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- Target
- CCM2 (Cerebral Cavernous Malformation 2 (CCM2))
- Andere Bezeichnung
- CCM2 (CCM2 Produkte)
- Synonyme
- C7orf22 antikoerper, OSM antikoerper, malcavernin antikoerper, CCM2 antikoerper, BC029157 antikoerper, TUF2 antikoerper, vtn antikoerper, zgc:110233 antikoerper, CCM2 scaffolding protein antikoerper, cerebral cavernous malformation 2 antikoerper, malcavernin antikoerper, CCM2 antikoerper, Ccm2 antikoerper, LOC100304744 antikoerper, ccm2 antikoerper
- Hintergrund
- This gene encodes a scaffold protein that functions in the stress-activated p38 Mitogen-activated protein kinase (MAPK) signaling cascade. The protein interacts with SMAD specific E3 ubiquitin protein ligase 1 (also known as SMURF1) via a phosphotyrosine binding domain to promote RhoA degradation. The protein is required for normal cytoskeletal structure, cell-cell interactions, and lumen formation in endothelial cells. Mutations in this gene result in cerebral cavernous malformations. Multiple transcript variants encoding different isoforms have been found for this gene.
- Molekulargewicht
- 48.7 kDa
- Gen-ID
- 83605
- NCBI Accession
- NM_031443
- HGNC
- 83605
- Pathways
- Cell-Cell Junction Organization
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