GTF2IRD1 Antikörper

Produktnummer ABIN272259

Produktdetails anti-GTF2IRD1 Antikörper

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GTF2IRD1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of WBSCR11 protein. (region surrounding Lys94)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu GTF2IRD1

Target: GTF2IRD1 (General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1))

Andere Bezeichnung: GTF2IRD1 / CREAM1 (GTF2IRD1 Produkte)

Synonyme: Gtf3 antikoerper, 1700012P16Rik antikoerper, BEN antikoerper, Cream1 antikoerper, ESTM9 antikoerper, GTF3 antikoerper, Gtf2il antikoerper, MusTRD1 antikoerper, Tg(Alb1-Myc)166.8Sst antikoerper, WBSCR11 antikoerper, X83320 antikoerper, GTF2IRD1 antikoerper, CREAM1 antikoerper, MUSTRD1 antikoerper, RBAP2 antikoerper, WBS antikoerper, WBSCR12 antikoerper, hMusTRD1alpha1 antikoerper, XBEN antikoerper, XWBSCR11 antikoerper, cream1 antikoerper, gtf3 antikoerper, mustrd1 antikoerper, rbap2 antikoerper, wbs antikoerper, wbscr11 antikoerper, wbscr12 antikoerper, GTF2I repeat domain containing 1 antikoerper, general transcription factor II I repeat domain-containing 1 antikoerper, general transcription factor II-I repeat domain-containing protein 1 antikoerper, GTF2I repeat domain containing 1 S homeolog antikoerper, GTF2IRD1 antikoerper, Gtf2ird1 antikoerper, gtf2ird1 antikoerper, LOC100461122 antikoerper, gtf2ird1.S antikoerper

Hintergrund: Williams-Beuren syndrome (WBS) is a developmental disorder caused by the hemizygous microdeletion on chromosome 7q11.23. WBS is an autosomal dominant genetic condition that is characterized by physical, cognitive and behavioral traits. The physical traits associated with WBS include facial dysmorphology, vascular stenoses, growth deficiencies, dental anomalies and neurologic and musculoskeletal abnormalities. Mild retardation, a weakness in visual-spatial skills, anxiety and a short attention span are typical cognitive and behavioral traits of WBS patients. The WBSCR11 gene is located within the WBS deletion and may contribute to the developmental symptoms found in WBS because of a loss of the encoded transcription factor. WBSCR11 is also designated GRF2IRD1, GTF3, Cream1 and MusTRD1 in human and BEN in mouse, due to slight differences in gene structure. WBSCR11 is expressed in all adult tissues as several variants and has discrete spatial and temporal expression during embryogenesis.Synonyms: GTF2I repeat domain-containing protein 1, GTF2I repeat domain-containing protein 1, GTF3, General transcription factor II-I repeat domain-containing protein 1, General transcription factor III, MUSTRD1, MusTRD1/BEN, Muscle TFII-I repeat domain-containing protein 1, RBAP2, Slow-muscle-fiber enhancer-binding protein, USE B1-binding protein, WBSCR11, WBSCR12, Williams-Beuren syndrome chromosomal region 11 protein

Molekulargewicht: approx. 106 kDa

Gen-ID: 9569

NCBI Accession: NP_001186136

UniProt: Q9UHL9