CDKL1 Antikörper

Produktnummer ABIN272207

Produktdetails anti-CDKL1 Antikörper

Target: CDKL1 (Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CDKL1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of KKIALRE protein. (region surrounding asn301)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Rat.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu CDKL1

Target: CDKL1 (Cyclin-Dependent Kinase-Like 1 (CDC2-Related Kinase) (CDKL1))

Andere Bezeichnung: CDKL1 (CDKL1 Produkte)

Synonyme: CDKL1 antikoerper, KKIALRE antikoerper, P42 antikoerper, 4933411O17Rik antikoerper, cyclin dependent kinase like 1 antikoerper, cyclin-dependent kinase-like 1 (CDC2-related kinase) antikoerper, CDKL1 antikoerper, cdkl1 antikoerper, Cdkl1 antikoerper

Hintergrund: The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.Synonyms: Cyclin-dependent kinase-like 1, KKIALRE, Protein kinase p42 KKIALRE, Serine/threonine-protein kinase KKIALRE

Molekulargewicht: approx. 42 kDa

Gen-ID: 8814

NCBI Accession: NP_004187

UniProt: Q00532