GAS41 Antikörper

Produktnummer ABIN272151

Produktdetails anti-GAS41 Antikörper

Target: GAS41 (YEATS Domain Containing 4)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GAS41 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of GAS41 protein. (region surrounding Arg32)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GAS41

Target: GAS41 (YEATS Domain Containing 4)

Andere Bezeichnung: YEATS4 (GAS41 Produkte)

Synonyme: 4930573H17Rik antikoerper, B230215M10Rik antikoerper, GAS41 antikoerper, NUBI-1 antikoerper, YAF9 antikoerper, YEATS4 antikoerper, NuBI-1 antikoerper, RGD1305741 antikoerper, zgc:100841 antikoerper, MGC89432 antikoerper, CG9207 antikoerper, Dmel\\CG9207 antikoerper, dGas41 antikoerper, GB13136 antikoerper, GLIOMAS 41 antikoerper, K2N11.8 antikoerper, K2N11_8 antikoerper, TAF14B antikoerper, TBP-ASSOCIATED FACTOR 14B antikoerper, NV13456 antikoerper, YEATS domain containing 4 antikoerper, YEATS domain containing 4 S homeolog antikoerper, CG9207 gene product from transcript CG9207-RA antikoerper, YEATS domain-containing protein 4 antikoerper, YEATS family protein antikoerper, Gas41 antikoerper, gas41 homologue, putative antikoerper, putative gas41 antikoerper, YEATS4 antikoerper, Yeats4 antikoerper, yeats4.S antikoerper, yeats4 antikoerper, Gas41 antikoerper, LOC412705 antikoerper, GAS41 antikoerper, Chro.20029 antikoerper, PB300718.00.0 antikoerper, PCHAS_122420 antikoerper, Smp_070760 antikoerper, LOC100121822 antikoerper

Hintergrund: Gene amplification is associated with tumor stage and progression in human gliomas. Several amplified loci are identified and comprise multiple genes. The glioma amplified sequence 41 (GAS41) is an evolutionarily conserved eukaryotic protein found in diverse species. GAS41 is related to the AF-9 and ENL proteins, which are putative transcription factors in some acute leukemias,and interacts with a component of the nuclear matrix, NuMA, in interphase cells. GAS41 has a dotted staining pattern in interphase nuclei and a uniform distribution in mitotic cells. GAS41 is ubiquitously expressed, with the highest levels of expression in human brain. In neuroblastoma, GAS41 is located in the nucleoli, but not in the nucleoplasm. GAS41 also binds to the MLL fusion partner AF-10, which is involved in two distinct chromosomal translocations associated with hematologic malignancy. In addition, GAS41 interacts with INI1 (integrase interactor 1), which is a human homolog of the yeast Snf5 protein, a component of the SWI/SNF complex. The GAS41 gene maps to human chromosome 12q13-q15.Synonyms: GAS41, Glioma-amplified sequence 41, NuBI-1, NuBI1, NuMA-binding protein 1, YEATS domain-containing protein 4

Molekulargewicht: approx. 42 kDa

Gen-ID: 8089

NCBI Accession: NP_006521

UniProt: O95619