KLF11 Antikörper

Produktnummer ABIN272134

Produktdetails anti-KLF11 Antikörper

Target: KLF11 (Kruppel-Like Factor 11 (KLF11))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KLF11 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of TIEG2 protein. (region surrounding Phe6)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Mouse.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu KLF11

Target: KLF11 (Kruppel-Like Factor 11 (KLF11))

Andere Bezeichnung: KLF11 / TIEG2 (KLF11 Produkte)

Synonyme: FKLF antikoerper, FKLF1 antikoerper, MODY7 antikoerper, TIEG2 antikoerper, Tieg3 antikoerper, 9830142A17 antikoerper, D12Ertd427e antikoerper, Tieg2 antikoerper, Tieg2b antikoerper, Tcfcp2l2 antikoerper, KLF11 antikoerper, klf11 antikoerper, si:dkey-81b15.5 antikoerper, tieg3 antikoerper, wu:fc45c07 antikoerper, wu:fj44b12 antikoerper, zgc:153255 antikoerper, fklf antikoerper, fklf1 antikoerper, mody7 antikoerper, tieg2 antikoerper, MGC145216 antikoerper, TIEG-2 antikoerper, zgc:154048 antikoerper, Kruppel like factor 11 antikoerper, Kruppel-like factor 11 antikoerper, Kruppel-like factor 11 L homeolog antikoerper, Kruppel-like factor 11a antikoerper, Krueppel-like factor 11 antikoerper, Kruppel-like factor 11b antikoerper, KLF11 antikoerper, Klf11 antikoerper, klf11.L antikoerper, klf11a antikoerper, klf11 antikoerper, LOC100194692 antikoerper, klf11b antikoerper

Hintergrund: Originally isolated from osteoblastic cells, the TGF-beta-inducible early gene-1 (TIEG1) is a Krupel-like zinc finger transcription factor-encoding gene which regulates cellular growth and differentiation. TIEG1 is regulated as an early response gene by TGFβ1. It is expressed in both acinar and ductular epithelial cells from exocrine pancreas and may serve as an early response gene in pancreatic cell lines. Further, overexpression of TIEG1 in TGFβ-sensitive epithelial cells induces apoptosis. TIEG1 and EGR-α are expressedfrom alternate promoters of the same gene. TIEG1 and EGR-α are both highly expressed in human fetal osteoblast cells. TIEG1 is additionally expressed at high levels in PBLs, spleen and colon, and at lower levels in thymus, small intestine, ovary, prostate and skeletal muscle. The nuclear TIEG2 protein, which shares significant homology with TIEG1, was originally isolated from globin-expressing human fetal eryth-roid cells. TIEG2 is also expressed in fetal liver. Overexpression of TIEG2 in cultured epithelial cells inhibits cellular proliferation, TIEG2 expression is upregulated by TGFβ1 and serum deprivation.Synonyms: FKLF, Krueppel-like factor 11, TGFB-inducible early growth response protein 2, TIEG-2, Transforming growth factor-beta-inducible early growth response protein 2

Molekulargewicht: approx. 55 kDa

Gen-ID: 8462

NCBI Accession: NP_001171187

UniProt: O14901