TGFB2 Antikörper

Produktnummer ABIN271850

Produktdetails anti-TGFB2 Antikörper

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFB2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of TGF beta-2 protein.

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen.

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TGFB2

Target: TGFB2 (Transforming Growth Factor, beta 2 (TGFB2))

Andere Bezeichnung: TGF-beta-2 (TGFB2) (TGFB2 Produkte)

Synonyme: LDS4 antikoerper, TGF-beta2 antikoerper, tgf-beta2 antikoerper, tgfb2-A antikoerper, BB105277 antikoerper, Tgf-beta2 antikoerper, Tgfb-2 antikoerper, TGF-beta 2 antikoerper, Tgfbr2T antikoerper, TGFB2 antikoerper, TGFbeta2 antikoerper, MGF antikoerper, TGF-B2 antikoerper, transforming growth factor beta 2 antikoerper, transforming growth factor beta 2 L homeolog antikoerper, transforming growth factor, beta 2 antikoerper, transforming growth factor, beta receptor 2 antikoerper, TGFB2 antikoerper, tgfb2.L antikoerper, Tgfb2 antikoerper, Tgfbr2 antikoerper, tgfb2 antikoerper

Hintergrund: Transforming growth factor betas (TGFβs) were originally discovered due to their ability to promote anchorage-independent growth of rat NRK fibroblasts in the presence of TGFα. It is now realized that TGFβs mediate many cell-cell interactions that occur during embryonic development. Three TGFβs have been identified in mammals. TGFβ1, TGFβ2 and TGFβ3 are each synthesized as precursor proteins that are very similar in that each is cleaved to yield a 112 amino acid polypeptide that remains associated with the latent portion of the molecules. Biologically active TGFβ requires dimerization of the monomers (usually homodimers) and release of the latent peptide portion. Overall, the mature region of the TGFβ3 protein has approximately 80 % identity to the mature region of both TGFβ1 and TGFβ2. However, the NH2 terminals or precursor regions of their molecules share only 27 % sequence identity.Synonyms: BSC-1 cell growth inhibitor, Cetermin, G-TSF, Glioblastoma-derived T-cell suppressor factor, Polyergin, Transforming growth factor beta-2

Gen-ID: 7042

NCBI Accession: NP_001129071

UniProt: P61812

Pathways: Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response, Protein targeting to Nucleus