TGFBR2 Antikörper

Produktnummer ABIN271848

Produktdetails anti-TGFBR2 Antikörper

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TGFBR2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of TGF beta Receptor II protein. (region surrounding Ile122)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu TGFBR2

Target: TGFBR2 (Transforming Growth Factor, beta Receptor II (70/80kDa) (TGFBR2))

Andere Bezeichnung: TGFBR2 (TGFBR2 Produkte)

Synonyme: AAT3 antikoerper, FAA3 antikoerper, LDS1B antikoerper, LDS2B antikoerper, MFS2 antikoerper, RIIC antikoerper, TAAD2 antikoerper, TGFR-2 antikoerper, TGFbeta-RII antikoerper, 1110020H15Rik antikoerper, AU042018 antikoerper, DNIIR antikoerper, RIIDN antikoerper, TBR-II antikoerper, TbetaR-II antikoerper, TbetaRII antikoerper, TGFBR2 antikoerper, TBETA-RII antikoerper, TGFBRII antikoerper, TGF-beta 2 antikoerper, Tgfbr2T antikoerper, cb537 antikoerper, tgfbr2 antikoerper, wu:fj05c10 antikoerper, zgc:110498 antikoerper, transforming growth factor beta receptor 2 antikoerper, transforming growth factor, beta receptor II antikoerper, transforming growth factor, beta receptor 2 antikoerper, transforming growth factor beta receptor 2b antikoerper, TGFBR2 antikoerper, Tgfbr2 antikoerper, tgfbr2b antikoerper

Hintergrund: A total of three members of the TGFbeta family, TGFbeta1, TGFbeta2 and TGFbeta3, have been identified in mammals. Each is synthesized as a latent precursor that is subsequently cleaved forming the 112 amino acid growth factor which becomes active upon dimerization. TGFbetas mediate their activity by high affinity binding to the type II receptor (TGFbeta RII) transmembrane protein with a cytoplasmic serine-threonine kinase domain. For signaling growth inhibition and early gene responses the type II receptor requires both its kinase activity and association with a TGFbeta-binding protein, designated the type I receptor. Two independent groups have recently described the cloning and sequence analysis of genes encoding TGFβ type I receptor proteins designated ALK-5 (TbetaR-1) and TSR-1, respectively.Synonyms: TGF-beta receptor type II, TGF-beta receptor type-2, TGF-beta type II receptor, TGFR-2, TbetaR-II, Transforming growth factor-beta receptor type II

Molekulargewicht: approx. 65.0 kDa

Gen-ID: 7048

NCBI Accession: NP_001020018

UniProt: P37173