IRF2 Antikörper (AA 81-180) (Alexa Fluor 488)

Produktnummer ABIN2690176

Produktdetails anti-IRF2 Antikörper (Alexa Fluor 488)

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Bindungsspezifität: AA 81-180

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IRF2 Antikörper ist konjugiert mit Alexa Fluor 488

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Cow,Sheep,Pig,Horse

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRF2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Andere Bezeichnung: IRF2 (IRF2 Produkte)

Synonyme: IRF-2 antikoerper, 9830146E22Rik antikoerper, AI646973 antikoerper, Irf-2 antikoerper, irf2b antikoerper, zgc:103451 antikoerper, irf-2 antikoerper, wu:fc74h04 antikoerper, zgc:76951 antikoerper, interferon regulatory factor 2 antikoerper, interferon regulatory factor 2 L homeolog antikoerper, interferon regulatory factor 2a antikoerper, IRF2 antikoerper, Irf2 antikoerper, irf2 antikoerper, irf2.L antikoerper, irf2a antikoerper

Hintergrund:

Synonyms: IRF-2, Interferon regulatory factor 2, IRF2

Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

Gen-ID: 3660

UniProt: P14316