TCP1 alpha/CCTA Antikörper

Produktnummer ABIN2666194

Produktdetails anti-TCP1 alpha/CCTA Antikörper

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser TCP1 alpha/CCTA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Kreuzreaktivität (Details): Recognizes ΔN-isoforms

Aufreinigung: The antibody was purified by antigen-affinity chromatography.

Klon: Poly6190

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Upon receipt, store frozen at -20°C.

Details zu TCP1 alpha/CCTA

Target: TCP1 alpha/CCTA (TCP1) (T-Complex 1 (TCP1))

Andere Bezeichnung: p63 (TCP1 Produkte)

Synonyme: CCT-alpha antikoerper, CCT1 antikoerper, CCTa antikoerper, D6S230E antikoerper, TCP-1-alpha antikoerper, AI528772 antikoerper, CCT antikoerper, Cct1 antikoerper, Ccta antikoerper, TRic antikoerper, Tcp-1 antikoerper, Tp63 antikoerper, c-cpn antikoerper, p63 antikoerper, TRiC antikoerper, CCTalpha antikoerper, BEST:GH05123 antikoerper, CG5374 antikoerper, Dmel\\CG5374 antikoerper, T-cpl antikoerper, TCP-1alpha antikoerper, TCPA_DROME antikoerper, Tcp1 antikoerper, Tcp1-alpha antikoerper, gh05123 antikoerper, cct-alpha antikoerper, ccta antikoerper, tcp1 antikoerper, tcp1-a antikoerper, tcp1a antikoerper, tcp1alpha antikoerper, CHUNP6875 antikoerper, fa13h08 antikoerper, wu:fa13h08 antikoerper, wu:fc95g06 antikoerper, t-complex 1 antikoerper, T-complex protein 1 subunit alpha antikoerper, t-complex protein 1 antikoerper, Tcp1-like antikoerper, t-complex 1 S homeolog antikoerper, TCP1 antikoerper, cct-1 antikoerper, Tcp1 antikoerper, T-cp1 antikoerper, tcp1.S antikoerper, tcp1 antikoerper

Hintergrund: P63 (ΔN) is a member of the p53 family. This protein has multiple isoforms TA p63-α, -β, γ, ΔN p63-α, -β, and -γ. The molecular weights of the p63 isoforms α=66 kD, β=52 kD, and γ=45 kD. This nuclear protein is essential for limb formation, epidermal morphogenesis, and epithelial stem cell regeneration. δN isoforms are antagonistic to p53, TA isoforms can transactivate p53 targets. The p63 ΔN isoforms repress TA isoforms, mutant p53 abrogates p63 transactivation. This protein interacts with p53, p73, and the various TA- and ΔN isoforms. The Poly6190 antibody recognizes human p63 ΔN isoforms and has been shown to be useful for Western blotting.