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CD28 Antikörper

CD28 Reaktivität: Human FACS Wirt: Maus Monoclonal CD28-2 unconjugated
Produktnummer ABIN2665975
  • Target Alle CD28 Antikörper anzeigen
    CD28
    Reaktivität
    • 181
    • 129
    • 60
    • 38
    • 21
    • 20
    • 12
    • 12
    • 7
    • 7
    • 6
    • 5
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human
    Wirt
    • 143
    • 78
    • 28
    • 18
    • 8
    • 3
    • 2
    Maus
    Klonalität
    • 200
    • 74
    • 3
    Monoklonal
    Konjugat
    • 93
    • 30
    • 28
    • 20
    • 15
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser CD28 Antikörper ist unkonjugiert
    Applikation
    • 204
    • 94
    • 50
    • 49
    • 39
    • 30
    • 30
    • 26
    • 21
    • 17
    • 13
    • 7
    • 7
    • 6
    • 6
    • 5
    • 4
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Flow Cytometry (FACS)
    Marke
    Ultra-LEAF™
    Kreuzreaktivität
    Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Pigtailed Macaque, Capuchin Monkey, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.)
    Aufreinigung
    The Ultra-LEAF™ (Low Endotoxin, Azide-Free) antibody was purified by affinity chromatography.
    Sterilität
    0.2 μm filtered
    Endotoxin-Niveau

    Endotoxin level is <0.01 EU/μg of the protein (<0.001 ng/μg of the protein) as determined by the LAL test.

    Klon
    CD28-2
    Isotyp
    IgG1 kappa
    Top Product
    Discover our top product CD28 Primärantikörper
  • Applikationshinweise
    Optimal working dilution should be determined by the investigator.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Konzentration
    1.0 mg/mL
    Konservierungsmittel
    Azide free
    Handhabung
    This Ultra-LEAF™ solution contains no preservative, handle under aseptic conditions
    Lagerung
    4 °C
    Informationen zur Lagerung
    The antibody solution should be stored undiluted between 2°C and 8°C.
  • Target
    CD28
    Andere Bezeichnung
    CD28 (CD28 Produkte)
    Synonyme
    Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
    Hintergrund
    CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
    Pathways
    T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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