TCR V Alpha24-J Alpha18 Antikörper
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- Target
- TCR V Alpha24-J Alpha18
- Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Unkonjugiert
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Applikation
- Flow Cytometry (FACS)
- Kreuzreaktivität
- Pigtailed Macaque, Sooty mangabey (Cercocebus atys), Rhesusaffen
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- 6B11
- Isotyp
- IgG1 kappa
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anti-TCR V Alpha24-J Alpha18 antibody (FITC)
Reaktivität: Human FACS Wirt: Maus Monoclonal 6B11 FITC
anti-TCR V Alpha24-J Alpha18 antibody (PE)Reaktivität: Human BCA Wirt: Maus Monoclonal 6B11 PE
anti-TCR V Alpha24-J Alpha18 antibody (PE-Cy7)Reaktivität: Human FACS Wirt: Maus Monoclonal 6B11 PE-Cy7
anti-TCR V Alpha24-J Alpha18 antibody (APC)Reaktivität: Human ELISA (Capture) Wirt: Maus Monoclonal 6B11 APC
anti-TCR V Alpha24-J Alpha18 antibody (PerCP-Cy5.5)Reaktivität: Human FACS Wirt: Maus Monoclonal 6B11 PerCP-Cy5.5
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- TCR V Alpha24-J Alpha18
- Hintergrund
- Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα 24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.
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