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P2RX7 Antikörper
P2RX7
Reaktivität: Maus
FACS
Wirt: Ratte
Monoclonal
1F11
unconjugated
Produktnummer ABIN2665313
Produktdetails anti-P2RX7 Antikörper
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Target
Alle P2RX7 Antikörper anzeigen
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Reaktivität
Alle Reaktivitäten für P2RX7 Antikörper
Maus
Wirt
Alle Wirte für P2RX7 Antikörper
Ratte
Klonalität
Alle Klonalitäten für P2RX7 Antikörper
Monoklonal
Konjugat
Alle Konjugate für P2RX7 Antikörper
Dieser P2RX7 Antikörper ist unkonjugiert
Applikation
Alle Applikationen für P2RX7 Antikörper
Flow Cytometry (FACS)
Aufreinigung
The antibody was purified by affinity chromatography.
Klon
1F11
Isotyp
IgG2b kappa
Top Product
Discover our top product P2RX7 Primärantikörper
Alternativen
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anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (N-Term) antibody
P2RX7
Reaktivität: Human, Maus, Ratte, Hund, Rind (Kuh), Pferd, Kaninchen, Meerschweinchen
WB, IHC
Wirt: Kaninchen
Polyclonal
unconjugated
anti-Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7) (AA 136-152), (Extracellular Loop) antibody
P2RX7
Reaktivität: Human, Maus, Ratte
WB, IHC, FACS, IF, ICC, LCI
Wirt: Kaninchen
Polyclonal
unconjugated
Anwendungsinformationen
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Applikationshinweise
Optimal working dilution should be determined by the investigator.
Beschränkungen
Nur für Forschungszwecke einsetzbar
Handhabung
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Konzentration
0.5 mg/mL
Buffer
Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
4 °C
Informationen zur Lagerung
The antibody solution should be stored undiluted between 2°C and 8°C.
Details zu P2RX7
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Target
P2RX7
(Purinergic Receptor P2X, Ligand-Gated Ion Channel, 7 (P2RX7))
Andere Bezeichnung
P2X7R (P2RX7 Produkte )
Synonyme
p2xr7 antikoerper, P2RX7 antikoerper, P2X7 antikoerper, AI467586 antikoerper, P2X(7) antikoerper, P2X7R antikoerper, p2x7 antikoerper, purinergic receptor P2X 7 antikoerper, purinergic receptor P2X, ligand-gated ion channel, 7 antikoerper, P2X purinoceptor 7 antikoerper, P2RX7 antikoerper, p2rx7 antikoerper, LOC100458463 antikoerper, P2rx7 antikoerper
Hintergrund
P2X7R, also known as P2X7 receptor, belongs to the family of ligand-gated ion channel receptors. It is expressed on T cells, B cells, macrophages, and microglia. The receptor opens in the presence of extracellular ATP or NAD, leading to intracellular calcium mobilization. P2X7R activation requires higher concentrations of ATP compared to other P2X receptors. Longer stimulation results in larger pores, allowing passage of larger molecules. Activation of these molecules also leads to mitochondrial and cytoskeletal changes as well as IL-1β maturation and release. Ligation of P2X7 receptor can lead to membrane blebbing and cell death.
Pathways
Regulation of Leukocyte Mediated Immunity , Positive Regulation of Immune Effector Process , Synaptic Vesicle Exocytosis
Zuletzt angesehen
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