CD52 Antikörper

Produktnummer ABIN2664761

Produktdetails anti-CD52 Antikörper

Target: CD52

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD52 Antikörper ist unkonjugiert

Applikation: Immunofluorescence (IF)

Aufreinigung: The antibody was purified by affinity chromatography.

Klon: HI186

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu CD52

Target: CD52

Andere Bezeichnung: CD52 (CD52 Produkte)

Synonyme: CD52 antikoerper, AI463198 antikoerper, B7 antikoerper, B7-Ag antikoerper, CAMPATH-1 antikoerper, CLS1 antikoerper, MB7 antikoerper, CDW52 antikoerper, CE5 antikoerper, CD52 molecule antikoerper, CD52 antigen antikoerper, CD52 antikoerper, Cd52 antikoerper

Hintergrund: CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression. The HI186 antibody is useful for flow cytometry and immunohistochemistry.