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- Target Alle CD28 Antikörper anzeigen
- CD28
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Reaktivität
- Human
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Wirt
- Maus
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Klonalität
- Monoklonal
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Konjugat
- Dieser CD28 Antikörper ist unkonjugiert
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Applikation
- Biochemical Assay (BCA)
- Kreuzreaktivität
- Schimpanse, Pavian, Cynomolgus, Rhesusaffen, Pigtailed Macaque, Capuchin Monkey, Sooty mangabey (Cercocebus atys), Squirrel Monkey (Saimiri spec.)
- Aufreinigung
- The antibody was purified by affinity chromatography.
- Klon
- CD28-2
- Isotyp
- IgG1 kappa
- Top Product
- Discover our top product CD28 Primärantikörper
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anti-CD28 (CD28) (AA 1-120) antibody
CD28 Reaktivität: Human, Maus, Ratte FACS, WB, ELISA, IHC (fro), IF (p), IHC (p), IF (cc) Wirt: Kaninchen Polyclonal unconjugated
anti-CD28 (CD28) antibodyCD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibody (FITC)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 FITC
anti-CD28 (CD28) (AA 19-152) antibodyCD28 Reaktivität: Human FACS, ELISA Wirt: Kaninchen Monoclonal DM61 unconjugated Recombinant Antibody
anti-CD28 (CD28) antibodyCD28 Reaktivität: Human, Non-Human Primate FACS, WB, IP, Func, IHC (fro), ICC Wirt: Maus Monoclonal CD28-2 unconjugated
anti-CD28 (CD28) antibodyCD28 Reaktivität: Ratte FACS, IP Wirt: Maus Monoclonal JJ319 unconjugated
anti-CD28 (CD28) antibody (PE)CD28 Reaktivität: Ratte FACS Wirt: Maus Monoclonal JJ319 PE
anti-CD28 (CD28) antibody (APC)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 APC
anti-CD28 (CD28) antibody (PE)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PE
anti-CD28 (CD28) antibody (PerCP)CD28 Reaktivität: Human, Non-Human Primate FACS Wirt: Maus Monoclonal CD28-2 PerCP
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- Applikationshinweise
- Optimal working dilution should be determined by the investigator.
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Konzentration
- 1.0 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and EDTA.
- Konservierungsmittel
- Sodium azide
- Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- 4 °C
- Informationen zur Lagerung
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- CD28
- Andere Bezeichnung
- CD28 (CD28 Produkte)
- Synonyme
- Tp44 antikoerper, CD28RNA antikoerper, cd28 antikoerper, CD28 molecule antikoerper, CD28 antigen antikoerper, Cd28 molecule antikoerper, CD28 molecule L homeolog antikoerper, CD28 antikoerper, Cd28 antikoerper, cd28.L antikoerper
- Hintergrund
- CD28 is a 44 kD disulfide-linked homodimeric type I glycoprotein. It is a member of the immunoglobulin superfamily and is also known as T44 or Tp44. CD28 is expressed on most T lineage cells, NK cell subsets, and plasma cells. CD28 binds both CD80 and CD86 using a highly conserved motif MYPPY in the CDR3-like loop. CD28 is considered a major co-stimulatory molecule, inducing T lymphocyte activation and IL-2 synthesis, and preventing cell death. In vitro studies indicate that ligation of CD28 on T cells by CD80 and CD86 on antigen presenting cells provides a costimulatory signal required for T cell activation and proliferation.
- Pathways
- T-Zell Rezeptor Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response
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