LILRA2 Antikörper (PE)

Produktnummer ABIN2663611

Produktdetails anti-LILRA2 Antikörper (PE)

Target: LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LILRA2 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: 24

Isotyp: IgG2b kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu LILRA2

Target: LILRA2 (Leukocyte Immunoglobulin-Like Receptor, Subfamily A (With TM Domain), Member 2 (LILRA2))

Andere Bezeichnung: CD85h (LILRA2 Produkte)

Synonyme: CD85H antikoerper, ILT1 antikoerper, LIR-7 antikoerper, LIR7 antikoerper, leukocyte immunoglobulin like receptor A2 antikoerper, LILRA2 antikoerper

Hintergrund: CD85 is a group of Ig superfamily tansmembrane glycoproteins called Ig-Like Transcripts (ILTs) or Leukocyte Immunoglobulin-like Receptors (LIRs). It is composed of both activating and inhibitory isoforms. The activating subset of ILTs is characterized by containing short cytoplasmic domains and positively charged arginine residues, while the inhibitory isoforms display long cytoplasmic tails containing ITIM motifs. CD85h is a 69kD activating receptor, also known as ILT1, LIR-7, or LILRA2. ILT1 is found on the surface of monocytes/macrophages, dendritic cells, and at relatively low levels on granulocytes. It is also expression on a small subset of NK cells. ILT1 acts as an activating receptor through its association with Fc receptor γ chain.