TNFSF13 Antikörper (PE)

Produktnummer ABIN2663230

Produktdetails anti-TNFSF13 Antikörper (PE)

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Reaktivität: Maus

Wirt: Armenischer Hamster

Klonalität: Monoklonal

Konjugat: Dieser TNFSF13 Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Kreuzreaktivität: Human

Aufreinigung: The antibody was purified by affinity chromatography, and conjugated with PE under optimal conditions. The solution is free of unconjugated PE and unconjugated antibody.

Klon: A3D8

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 0.2 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C.

Details zu TNFSF13

Target: TNFSF13 (Tumor Necrosis Factor (Ligand) Superfamily, Member 13 (TNFSF13))

Andere Bezeichnung: CD256 (TNFSF13 Produkte)

Synonyme: APRIL antikoerper, CD256 antikoerper, TALL-2 antikoerper, TALL2 antikoerper, TRDL-1 antikoerper, ZTNF2 antikoerper, 2310026N09Rik antikoerper, April antikoerper, Tall2 antikoerper, Trdl1 antikoerper, SLAN antikoerper, ANP32B antikoerper, april antikoerper, tnf13 antikoerper, TNLG7B antikoerper, TNF superfamily member 13 antikoerper, tumor necrosis factor (ligand) superfamily, member 13 antikoerper, acidic leucine-rich nuclear phosphoprotein 32 family member B antikoerper, TNFSF13 antikoerper, Tnfsf13 antikoerper, LOC494442 antikoerper, tnfsf13 antikoerper

Hintergrund: CD256 (APRIL, TNFSF13, TALL2, TRDL1) a transmembranal protein of 26 kD, forms a homotrimeric molecule that is cleaved from the cell surface resulting in the soluble form of APRIL, it also forms heterotrimers with BLyS. Its receptor are TNFRSF13b/TACI and TNFRSF17/BCMA. Expressed by T cells, B cells, dendritic cells, monocytes, and macrophages, APRIL induces proliferation of T and B cells, promotes IgA class switching, downregulates T-cell dependent antibody responses, and regulates the growth of a variety of tumor cells.

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response