CD101 Antikörper (Alexa Fluor 647)

Produktnummer ABIN2657119

Produktdetails anti-CD101 Antikörper (Alexa Fluor 647)

Target: CD101

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD101 Antikörper ist konjugiert mit Alexa Fluor 647

Applikation: Flow Cytometry (FACS), Intracellular Flow Cytometry (ICFC)

Aufreinigung: The antibody was purified by affinity chromatography and conjugated with Alexa Fluor® 647 under optimal conditions.

Klon: BB27

Isotyp: IgG1 kappa

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide and 0.2 % (w/v) BSA .

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Protect from prolonged exposure to light. Do not freeze.

Lagerung: 4 °C

Informationen zur Lagerung: The antibody solution should be stored undiluted between 2°C and 8°C

Details zu CD101

Target: CD101

Andere Bezeichnung: CD101 (CD101 Produkte)

Synonyme: Gm1016 antikoerper, Gm734 antikoerper, Igsf2 antikoerper, EWI-101 antikoerper, IGSF2 antikoerper, V7 antikoerper, CD101 molecule antikoerper, CD101 antigen antikoerper, CD101 antikoerper, Cd101 antikoerper

Hintergrund: CD101 is a type I transmembrane glycoprotein also known as V7 and P126. It is a 120 kD homodimer and member of the EWI family within the Ig superfamily. CD101 is found on monocytes, granulocytes, dendritic cells, and a subpopulation of peripheral blood T cells and activated T cells. It has been reported that CD101 expressing Tregs possess higher inhibitory function. The biological function of CD101 is still not clear, but it has been found that BB27 antibody is able to inhibit T cell proliferative responses and this inhibitory function can be overcome by high doses of IL-2. Activation of CD101 on dendritic cells is able to induce IL-10 production.