MMP16 Antikörper

Produktnummer ABIN265527

Produktdetails anti-MMP16 Antikörper

Target: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MMP16 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of MMP-16 protein. (region surrounding Thr583)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu MMP16

Target: MMP16 (Matrix Metallopeptidase 16 (Membrane-inserted) (MMP16))

Andere Bezeichnung: MMP-16 (MMP16 Produkte)

Synonyme: MT3-MMP antikoerper, Mt3mmp antikoerper, Mt3-mmp antikoerper, C8orf57 antikoerper, MMP-X2 antikoerper, MT-MMP2 antikoerper, MT-MMP3 antikoerper, matrix metallopeptidase 16 antikoerper, Mmp16 antikoerper, MMP16 antikoerper

Hintergrund: The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen, gelatin, fibronectin, laminin and proteoglycan. Transcription of MMP genes is differentially activated by phorbol ester, lipopolysaccharide (LPS) or staphylococcal enterotoxin B (SEB). MMP catalysis requires both calcium and zinc. MMP-13 (also designated collagenase-3) is produced by breast carcinomas and degrades collagen types I, II and III. MMP-13 has wide substrate specificity, and its physiologic expression is limited to situations in which rapid and effective remodeling of collagenous ECM takes place, such as fetal bone development and adult bone remodeling.Synonyms: MMP-X2, MMP16, MMPX2, Matrix metalloproteinase-16, Membrane-type-3 matrix metalloproteinase

Molekulargewicht: approx. 68 kDa

Gen-ID: 4325

NCBI Accession: NP_005932

UniProt: P51512