Keratin 10 Antikörper

Produktnummer ABIN265492

Produktdetails anti-Keratin 10 Antikörper

Target: Keratin 10 (KRT10)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Keratin 10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Cytokeratin 10 protein. (region surrounding Tyr160)

Kreuzreaktivität (Details): Species reactivity (tested):Human, Maus, Rat.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 5000approx. 1: 10000. WB: 1: 500approx. 1: 1000. IF: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu Keratin 10

Target: Keratin 10 (KRT10)

Andere Bezeichnung: Cytokeratin 10 (KRT10 Produkte)

Synonyme: BCIE antikoerper, BIE antikoerper, CK10 antikoerper, EHK antikoerper, K10 antikoerper, KPP antikoerper, D130054E02Rik antikoerper, K1C1 antikoerper, Krt-1.10 antikoerper, Krt1-10 antikoerper, Ka10 antikoerper, Ker10 antikoerper, KRT10 antikoerper, KRT25 antikoerper, KRT27 antikoerper, KRT28 antikoerper, keratin 10 antikoerper, keratin 10, type I S homeolog antikoerper, keratin, type I cytoskeletal 25 antikoerper, KRT10 antikoerper, Krt10 antikoerper, krt10.S antikoerper, LOC101085587 antikoerper

Hintergrund: Cytokeratins comprise a diverse group of intermediate filament proteins (IFPs) that are expressed as pairs in both keratinized and non-keratinized epithelial tissue. Cytokeratins play a critical role in differentiation and tissue specialization and function to maintain the overall structural integrity of epithelial cells. Cytokeratins have been found to be useful markers of tissue differentiation which is directly applicable to the characterization of malignant tumors. Cytokeratins 10 and 13 are present in the cytoskeletal region of a subset of squamous cell carcinomas. Cytokeratin 10 is a heterotetramer of two type I and two type II keratins, is generally associated with keratin 1, and is seen in all suprabasal cell layers including stratum corneum.Synonyms: CK-10, CK10, Cytokeratin-10, K10, KPP, KRT10, Keratin, Keratin-10, Type I Cytoskeletal 10

Molekulargewicht: approx. 59 kDa

Gen-ID: 3858

NCBI Accession: NP_000412

UniProt: P13645