GRIK2 Antikörper

Produktnummer ABIN265439

Produktdetails anti-GRIK2 Antikörper

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRIK2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of GluR6 protein. (region surrounding Ala865)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 1 5000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: DO NOT FREEZE!

Lagerung: 4 °C

Informationen zur Lagerung: Store the antibody undiluted at 2-8 °C.

Details zu GRIK2

Target: GRIK2 (Glutamate Receptor, Ionotropic, Kainate 2 (GRIK2))

Andere Bezeichnung: Glutamate Receptor 6 / GLUR6 (GRIK2 Produkte)

Synonyme: GRIK5 antikoerper, eaa4 antikoerper, glr6 antikoerper, gluk6 antikoerper, glur6 antikoerper, grik2 antikoerper, mrt6 antikoerper, GluR6 antikoerper, grik2-A antikoerper, EAA4 antikoerper, GLR6 antikoerper, GLUK6 antikoerper, GLUR6 antikoerper, GluK2 antikoerper, MRT6 antikoerper, AW124492 antikoerper, Glur-6 antikoerper, Glur6 antikoerper, Glurbeta2 antikoerper, GRIK2 antikoerper, glutamate ionotropic receptor kainate type subunit 2 antikoerper, glutamate receptor, ionotropic, kainate 2 L homeolog antikoerper, glutamate receptor, ionotropic, kainate 2 antikoerper, glutamate receptor, ionotropic, kainate 2 (beta 2) antikoerper, GRIK2 antikoerper, grik2.L antikoerper, grik2 antikoerper, Grik2 antikoerper

Hintergrund: The mGluR proteins (metabotropic glutamate receptors) are members of the G protein-coupled receptor family and are functionally and pharmacologically distinct from the GluR proteins (ionotropic glutamate receptors). The eight currently known mGluR proteins are mediated by two G proteins with opposing regulation of adenylate cyclase pathways. The activities of mGluR-1 and mGluR-5 are mediated by a G protein that activates a phosphatidylinositolcalcium second messenger system and generates a calcium-activated chloride current. The remainder of the eight subtypes of mGluR have an activity mediated by a G protein that inhibits adenylate cyclase activity. mGluR-6 is expressed in the synapses of bipolar cell dendrites. This receptor is involved in mediating synaptic transmission from rod and cone photoreceptors to other neurons.Synonyms: EAA4, Excitatory amino acid receptor 4, GRIK2, Glutamate receptor ionotropic kainate 2

Molekulargewicht: approx. 100 kDa

Gen-ID: 2898

NCBI Accession: NP_001159719

UniProt: Q13002

Pathways: Synaptic Membrane, Regulation of long-term Neuronal Synaptic Plasticity