Cyclin G1 Antikörper

Produktnummer ABIN265382

Produktdetails anti-Cyclin G1 Antikörper

Target: Cyclin G1 (CCNG1)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin G1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Spezifität: This antibody detects endogenous levels of Cyclin G protein. (region surrounding Ile194)

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: Affinity Chromatography using epitope-specific immunogen

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu Cyclin G1

Target: Cyclin G1 (CCNG1)

Andere Bezeichnung: Cyclin G1 (CCNG1 Produkte)

Synonyme: CCNG antikoerper, AI314029 antikoerper, CYCG antikoerper, Ccng antikoerper, CG 11525 antikoerper, CG11525 antikoerper, Dmel\\CG11525 antikoerper, anon-EST:Liang-1.25 antikoerper, anon-EST:Liang-2.24 antikoerper, clone 1.25 antikoerper, clone 2.24 antikoerper, dCycG antikoerper, i205 antikoerper, i261 antikoerper, cb138 antikoerper, fd08g04 antikoerper, sb:cb138 antikoerper, wu:fb07e04 antikoerper, wu:fd08g04 antikoerper, zgc:56595 antikoerper, ccng1 antikoerper, cyclin G1 antikoerper, Cyclin G antikoerper, cyclin G1 S homeolog antikoerper, CCNG1 antikoerper, Ccng1 antikoerper, CycG antikoerper, ccng1 antikoerper, ccng1.S antikoerper

Hintergrund: Cyclins are the regulatory subunits of Cdc2 p34 and related cyclin-dependent kinases (Cdks) which play critical roles in the control of cell cycle progression. The catalytic subunit for cyclin A and B is Cdc2 p34 kinase. The Cdc2- cyclin B complex controls the G2 to M transition whereas Cdc2-cyclin A regulates S phase progression. The G1 to S transition, however, appears to be controlled by the G1 cyclins. Cyclin D1 accumulates during G1 and associates with Cdk2, Cdk4 and Cdk5. Cyclin E and Cdk2 interact during the G1 to S transition. Cyclin G contains a typical N terminal cyclin box and a carboxy terminal domain sequence homologous to the tyrosine phosphorylation site of the epidermal growth factor receptor. Cyclin G expression is induced within 3 hours after growth stimulation and remains elevated with no apparent cell cycle dependency. Cyclin G2 shares 53 % amino acid sequence identity with cyclin G1. Peak expression of cyclin G2 is seen in late S phase, as opposed to cyclin G1 expression, which is constitutive.Synonyms: CCNG, CCNG1, CYCG1, Cyclin-G, Cyclin-G1

Molekulargewicht: approx. 29 kDa

Gen-ID: 900

NCBI Accession: NP_004051

UniProt: P51959

Pathways: p53 Signalweg