CLDN10 Antikörper

Produktnummer ABIN265359

Produktdetails anti-CLDN10 Antikörper

Target: CLDN10 (Claudin 10 (CLDN10))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CLDN10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody detects endogenous levels of Claudin-10 / CLDN10 protein (region surrounding Asn217).

Kreuzreaktivität (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity chromatography using epitope-specific immunogen

Reinheit: > 95 % pure by SDS-PAGE

Anwendungsinformationen

Applikationshinweise: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Konzentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Details zu CLDN10

Target: CLDN10 (Claudin 10 (CLDN10))

Andere Bezeichnung: Claudin-10 / CLDN10 (CLDN10 Produkte)

Synonyme: si:busm1-52i16.3 antikoerper, si:dz52i16.3 antikoerper, CLDN10 antikoerper, DKFZp469F1626 antikoerper, CPETRL3 antikoerper, OSP-L antikoerper, 6720456I16Rik antikoerper, Cldn10a antikoerper, Cldn10b antikoerper, D14Ertd728e antikoerper, claudin 10a antikoerper, claudin 10 antikoerper, cldn10a antikoerper, CLDN10 antikoerper, Cldn10 antikoerper

Hintergrund: The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight junctions in paracellular transport. Claudins are located in both epithelial and endothelial cells in all tight junction-bearing tissues. Three classes of proteins are known to localize to tight junctions, including the Claudins, Occludin and junction adhesion molecule (JAM). Claudins, which consist of four transmembrane domains and two extracellular loops, make up tight junction strands. Emerging evidence suggests that the Claudin family of proteins regulates transport through tight junctions via differential discrimination for solute size and charge. Claudin expression is often highly restricted to specfic regions of different tissues and may have an important role in transcellular transport through tight junctions.Synonyms: OSP-Like Protein, OSPL

Molekulargewicht: approx. 25 kDa

Gen-ID: 9071

NCBI Accession: NP_008915

UniProt: P78369

Pathways: Hepatitis C