KCND2 Antikörper

Produktnummer ABIN265029

Produktdetails anti-KCND2 Antikörper

Target: KCND2 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KCND2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: This antibody reacts to Kv4.2 Potassium Channel.

Aufreinigung: Purified

Immunogen: Synthetic peptide derived from the rat Kv4.2 potassium channel conjugated to KLH.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 5 - 10 μg/mL.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: Phosphate buffered saline with 0.08 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: -20 °C

Informationen zur Lagerung: The antibody can be shipped at ambient temperature. Store (in aliquots) at -20 °C only.

Details zu KCND2

Target: KCND2 (Potassium Voltage-Gated Channel, Shal-Related Subfamily, Member 2 (KCND2))

Andere Bezeichnung: KCND2 (KCND2 Produkte)

Synonyme: KCND2 antikoerper, si:dkey-24j9.3 antikoerper, si:dkeyp-97c5.3 antikoerper, DKFZp459P1550 antikoerper, AI839615 antikoerper, AW555701 antikoerper, Kv4.2 antikoerper, R75121 antikoerper, mKIAA1044 antikoerper, KV4.2 antikoerper, RK5 antikoerper, Shal1 antikoerper, potassium voltage-gated channel subfamily D member 2 antikoerper, potassium voltage-gated channel, Shal-related subfamily, member 2 antikoerper, potassium voltage-gated channel, Shal-related family, member 2 antikoerper, KCND2 antikoerper, kcnd2 antikoerper, Kcnd2 antikoerper, LOC101669961 antikoerper

Hintergrund: The Kv4.2 potassium channel is a voltage-gated channel protein which belongs to the delayed rectifier class and to the Shal potassium channel subfamily. Potassium channels are mainly found in plasma membranes but are not generally distributed over the cell surface. Potassium channels catalyze the rapid permeation of potassium ions while rejecting biologically abundant potential competitors such as sodium, calcium and magnesium. Ion selectivity and high through put rate of potassium channels is accomplished by precise co-ordination of dehydrated potassium by the protein and multiple ion occupancy within the permeation pathway. All potassium channels carry out the formation of a transmembrane leak specific for potassium ions. Since cells almost universally maintain cytoplasmic potassium concentrations higher than those extracellularly, the opening of a potassium channel implies a negative ongoing change in electrical voltage across the cell membrane. This may result in termination of the action potential of electrically excitable cells including nerve, muscle and pancreatic beta cells. In non-excitable cells, potassium channels play important roles in the cellular potassium recycling required for electrolyte balance effected by the renal epithelium.Synonyms: KIAA1044, Potassium voltage-gated channel subfamily D member 2, Voltage-gated potassium channel subunit Kv4.2

Gen-ID: 3751

NCBI Accession: NP_036413

UniProt: Q9NZV8