CD1a Antikörper

Produktnummer ABIN2618409

Produktdetails anti-CD1a Antikörper

Target: CD1a

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser CD1a Antikörper ist unkonjugiert

Applikation: Flow Cytometry (FACS), Immunohistochemistry (IHC), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunocytochemistry (ICC)

Spezifität: The CBT6 antibody is directed against human CD1a and has been reported to cross react with mouse thymocytes.

Aufreinigung: Purified

Immunogen: CBT6 is a mouse monoclonal IgG1 antibody derived by the fusion of NS0 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a T-lymphocyte derived antigen.

Type of Immunogen: Cells

Klon: CBT6

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Approved: ELISA, Flo, ICC, IHC, IHC-Fr

Usage: CD1 Molecules are 49kD type 1 membrane glycoproteins that contain a single Ig-like domain, which associate with beta-2 microglobulin to form a heterodimer. The CD1 glycoproteins function as antigen-presenting molecules for exogenous and endogenous lipids, glycolipids and lipopeptides to specialized T cells. The CD1 Molecules show some sequence similarities to major histocompatibility (MHC) class I and class II molecules, but are not encoded by the MHC genes and are not significantly polymorphic. In humans, the CD1 genes encode five isoforms of CD1, namely CD1a-e, with each type reported to show a different pattern of expression on cells and within different tissues. CD1a, b and c belong to group 1 of the CD1 family and are expressed by dendritic cells, activated monocytes and other antigen-presenting cells. CD1a is also expressed by some malignancies of T cell lineage and is commonly used as a marker of dendritic cell populations.

Kommentare:

Target Species of Antibody: Human

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: PBS, 50 % glycerol, 0.2 % BSA, 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeat freeze-thaw cycles.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Details zu CD1a

Target: CD1a

Andere Bezeichnung: CD1A (CD1a Produkte)

Synonyme: CD1 antikoerper, FCB6 antikoerper, HTA1 antikoerper, R4 antikoerper, T6 antikoerper, CD1A antikoerper, CD1a molecule antikoerper, CD1 antigen antikoerper, T-cell surface glycoprotein CD1a antikoerper, CD1A antikoerper, CD1.1 antikoerper, LOC100156095 antikoerper, LOC101111409 antikoerper

Hintergrund: Name/Gene ID: CD1A

Synonyms: CD1A, CD1, CD1A antigen, a polypeptide, CD1a molecule, FCB6, HTA1, HTa1 thymocyte antigen, R4, T6, CD1a antigen, Cluster of differentiation 1 A

Gen-ID: 909

Pathways: Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process