VTI1b antibody is human, mouse and rat reactive. At least three isoforms of VTI1a are known to exist, this antibody will detect all three isoforms. VTI1b antibody is predicted to not cross-react with VTI1a.
Aufreinigung
VTI1b antibody is affinity chromatography purified via peptide column.
Immunogen
VTI1b antibody was raised against a 17 amino acid peptide near the center of human VTI1b.
VTI1 antikoerper, VTI1-LIKE antikoerper, VTI1L antikoerper, VTI2 antikoerper, v-SNARE antikoerper, vti1-rp1 antikoerper, AU015348 antikoerper, GES30 antikoerper, MVti1b antikoerper, SNARE antikoerper, Vti1-rp1 antikoerper, zgc:63525 antikoerper, VTI1B antikoerper, vesicle transport through interaction with t-SNAREs 1B antikoerper, vesicle transport through interaction with t-SNAREs 1B pseudogene antikoerper, VTI1B antikoerper, Vti1b antikoerper, vti1b antikoerper, LOC461624 antikoerper
Hintergrund
Vesicle transport through interaction with t-SNAREs homolog 1 (VTI1a and VTI1b) are involved in vesicular transport from the late endosomes to the trans-Golgi network (1). They are both localized in the trans-Golgi network, with VTI1a also found in the Golgi apparatus and VTI1b in endosomes (2,3). It is thought that VTI1b along with the SNARE protein VAMP8 mediates the fusion of antimicrobial and canonical autophagosomes with lysosomes, an essential process for autophagy (4).