Protein Tob1 (TOB1) (pSer164) Antikörper

Produktnummer ABIN2568512

Produktdetails

Target: Protein Tob1 (TOB1)

Bindungsspezifität: pSer164

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: The antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: TOB1 (phospho Ser164) antibody was raised against a peptide sequence around phosphorylation site of Serine 164 (A-V-S (p)-P-T) derived from Human TOB1.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Antigendetails

Target: Protein Tob1 (TOB1)

Andere Bezeichnung: TOB1 (TOB1 Produkte)

Synonyme: Tob antikoerper, Trob antikoerper, APRO5 antikoerper, APRO6 antikoerper, PIG49 antikoerper, TOB antikoerper, TROB antikoerper, TROB1 antikoerper, tob1 antikoerper, tob1l antikoerper, wu:fb54d02 antikoerper, wu:fb98h12 antikoerper, wu:fd15f10 antikoerper, zgc:65837 antikoerper, transducer of ErbB-2.1 antikoerper, transducer of ERBB2, 1 antikoerper, transducer of ERBB2, 1a antikoerper, transducer of ERBB2, 1 S homeolog antikoerper, transducer of ERBB2, 1b antikoerper, Tob1 antikoerper, TOB1 antikoerper, tob1a antikoerper, tob1.S antikoerper, tob1b antikoerper

Hintergrund: This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.

Molekulargewicht: 40 kDa

Gen-ID: 10140

NCBI Accession: NP_001230806

UniProt: P50616