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Protein Tob1 (TOB1) (pSer164) Antikörper

TOB1 Reaktivität: Human, Maus, Ratte WB, IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN2568512
  • Target Alle Protein Tob1 (TOB1) Antikörper anzeigen
    Protein Tob1 (TOB1)
    Bindungsspezifität
    • 15
    • 10
    • 10
    • 9
    • 8
    • 5
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    pSer164
    Reaktivität
    • 49
    • 31
    • 28
    • 5
    • 5
    • 5
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte
    Wirt
    • 63
    • 2
    Kaninchen
    Klonalität
    • 65
    Polyklonal
    Konjugat
    • 23
    • 6
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Unkonjugiert
    Applikation
    • 32
    • 26
    • 13
    • 13
    • 10
    • 8
    • 4
    • 4
    • 3
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (IHC)
    Spezifität
    The antibody detects endogenous levels of TOB1 only when phosphorylated at serine 164.
    Aufreinigung
    Antibodies were purified by affinity-chromatography using epitope-specific peptide.
    Immunogen
    TOB1 (phospho Ser164) antibody was raised against a peptide sequence around phosphorylation site of Serine 164 (A-V-S (p)-P-T) derived from Human TOB1.
    Isotyp
    IgG
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  • Applikationshinweise
    Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    1 mg/mL
    Buffer
    Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store antibody at -20°C for up to one year.
  • Target
    Protein Tob1 (TOB1)
    Andere Bezeichnung
    TOB1 (TOB1 Produkte)
    Synonyme
    Tob antikoerper, Trob antikoerper, APRO5 antikoerper, APRO6 antikoerper, PIG49 antikoerper, TOB antikoerper, TROB antikoerper, TROB1 antikoerper, tob1 antikoerper, tob1l antikoerper, wu:fb54d02 antikoerper, wu:fb98h12 antikoerper, wu:fd15f10 antikoerper, zgc:65837 antikoerper, transducer of ErbB-2.1 antikoerper, transducer of ERBB2, 1 antikoerper, transducer of ERBB2, 1a antikoerper, transducer of ERBB2, 1 S homeolog antikoerper, transducer of ERBB2, 1b antikoerper, Tob1 antikoerper, TOB1 antikoerper, tob1a antikoerper, tob1.S antikoerper, tob1b antikoerper
    Hintergrund
    This gene encodes a member of the tob/btg1 family of anti-proliferative proteins that have the potential to regulate cell growth. When exogenously expressed, this protein supresses cell growth in tissue culture. The protein undergoes phophorylation by a serine/threonine kinase, 90 kDa ribosomal S6 kinase. Interactions of this protein with the v-erb-b2 erythroblastic leukemia viral oncogene homolog 2 gene product p185 interferes with growth suppression. This protein inhibits T cell proliferation and transcription of cytokines and cyclins. The protein interacts with both mothers against decapentaplegic Drosophila homolog 2 and 4 to enhance their DNA binding activity. This interaction inhibits interleukin 2 transcription in T cells.
    Molekulargewicht
    40 kDa
    Gen-ID
    10140
    NCBI Accession
    NP_001230806
    UniProt
    P50616
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