RFX1 Antikörper

Produktnummer ABIN2568446

Produktdetails anti-RFX1 Antikörper

Target: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RFX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Spezifität: RFX1 antibody is human specific. At least two isoforms of RFX1 are known to exist, this antibody will detect both isoforms.

Aufreinigung: RFX1 antibody is affinity chromatography purified via peptide column.

Immunogen: RFX1 antibody was raised against an 18 amino acid peptide near the carboxy terminus of human RFX1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: RFX1 antibody can be used for detection of RFX1 by Western blot at 1 - 2 μ,g/mL.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: RFX1 antibody is supplied in PBS containing 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C,4 °C

Informationen zur Lagerung: RFX1 antibody can be stored at 4°C for three months and -20°C, stable for up to one year.

Details zu RFX1

Target: RFX1 (Regulatory Factor X, 1 (Influences HLA Class II Expression) (RFX1))

Andere Bezeichnung: RFX1 (RFX1 Produkte)

Synonyme: EFC antikoerper, RFX antikoerper, AI047719 antikoerper, AI385641 antikoerper, zgc:162914 antikoerper, regulatory factor X1 antikoerper, regulatory factor X, 1 (influences HLA class II expression) antikoerper, regulatory factor X, 1a (influences HLA class II expression) antikoerper, RFX1 antikoerper, Rfx1 antikoerper, rfx1a antikoerper

Hintergrund: RFX1 is a member of the regulatory factor X protein family, which are transcription factors that contain a highly-conserved winged helix DNA binding domain and the D region found in the C-terminal part of these proteins which facilitates dimerization (1,2). RFX1 is structurally related to regulatory factors X2, X3, X4, and X5 (3). RFX1 is a regulatory factor essential for MHC class II genes expression and can bind to an inverted repeat that is required for expression of hepatitis B virus genes (4). Recent study identifies RFX1 may play a tumor suppressor role in HCC as autophagy mediator (5).

Molekulargewicht: Predicted: 108 kDa

Observed: 125 kDa

Gen-ID: 5989

NCBI Accession: NP_002909

UniProt: P22670