PEA15 Antikörper (pSer104)

Produktnummer ABIN2568425

Produktdetails anti-PEA15 Antikörper

Target: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Bindungsspezifität: pSer104

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEA15 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Spezifität: The antibody detects endogenous levels of PEA-15 only when phosphorylated at serine 104.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: PEA-15 (phospho Ser104) antibody was raised against a peptide sequence around phosphorylation site of Serine 104 (I-P-S (p)-A-K) derived from Human PEA-15.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000, Immunohistochemistry: 1:50~1:100

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu PEA15

Target: PEA15 (phosphoprotein Enriched in Astrocytes 15 (PEA15))

Andere Bezeichnung: PEA-15 (PEA15 Produkte)

Synonyme: HMAT1 antikoerper, HUMMAT1H antikoerper, MAT1 antikoerper, MAT1H antikoerper, PEA-15 antikoerper, PED antikoerper, Pea15a antikoerper, PEA15 antikoerper, DKFZp459O1410 antikoerper, proliferation and apoptosis adaptor protein 15 antikoerper, phosphoprotein enriched in astrocytes 15 antikoerper, proliferation and apoptosis adaptor protein 15 L homeolog antikoerper, Astrocytic phosphoprotein PEA-15 antikoerper, PEA15 antikoerper, Pea15 antikoerper, pea15.L antikoerper, pea15 antikoerper

Hintergrund: Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm. Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptosis. Regulates glucose transport by controlling both the content of SLC2A1 glucose transporters on the plasma membrane and the insulin-dependent trafficking of SLC2A4 from the cell interior to the surface.

Molekulargewicht: 19 kDa

Gen-ID: 8682

NCBI Accession: NP_003759

UniProt: Q15121