RACGAP1 Antikörper (pSer387)

Produktnummer ABIN2568176

Produktdetails anti-RACGAP1 Antikörper

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Bindungsspezifität: pSer387

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser RACGAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The antibody detects endogenous level of GTPase Activating Protein only when phosphorylated at serine 387.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: GTPase Activating Protein (phospho Ser387) antibody was raised against a peptide sequence around phosphorylation site of serine 387 (R-I-S (p)-G-C) derived from Human GTPase Activating Protein.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu RACGAP1

Target: RACGAP1 (Rac GTPase Activating Protein 1 (RACGAP1))

Andere Bezeichnung: GTPase Activating Protein (RACGAP1 Produkte)

Synonyme: CYK4 antikoerper, HsCYK-4 antikoerper, ID-GAP antikoerper, MgcRacGAP antikoerper, cyk-4 antikoerper, id-gap antikoerper, mgcracgap antikoerper, RACGAP1 antikoerper, MGC121578 antikoerper, Gap antikoerper, RasGAP antikoerper, Rasa antikoerper, GAPX antikoerper, AI227039 antikoerper, AI327394 antikoerper, Band25 antikoerper, GTPase antikoerper, gtl11 antikoerper, mKIAA1478 antikoerper, wu:fb92c08 antikoerper, zgc:77839 antikoerper, Rac GTPase activating protein 1 antikoerper, rac GTPase-activating protein 1 antikoerper, Rac GTPase activating protein 1 L homeolog antikoerper, RAS p21 protein activator 1 antikoerper, Rac GTPase-activating protein 1 antikoerper, si:ch1073-416j23.1 antikoerper, RACGAP1 antikoerper, racgap1 antikoerper, racgap1.L antikoerper, racgap1.2.L antikoerper, racgap1.2 antikoerper, Rasa1 antikoerper, Racgap1 antikoerper, si:ch1073-416j23.1 antikoerper

Hintergrund: Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation.

Molekulargewicht: 72 kDa

Gen-ID: 29127

NCBI Accession: NP_001119575

UniProt: Q9H0H5

Pathways: Regulation of Actin Filament Polymerization, Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, Signaling of Hepatocyte Growth Factor Receptor