CEBPA Antikörper (pThr230)

Produktnummer ABIN2567076

Produktdetails anti-CEBPA Antikörper

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Bindungsspezifität: pThr230

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CEBPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Spezifität: The Antibody detects endogenous levels of C/EBP-alpha only when phosphorylated at Thr230.

Aufreinigung: Antibodies were purified by affinity-chromatography using epitope-specific peptide.

Immunogen: C/EBP-alpha (phospho Thr230) antibody was raised against a peptide sequence around phosphorylation site of threonine 230 (P-P-T (p)-P-V) derived from Human C/EBP-alpha.

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Western Blot: 1:500~1:1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Antibody supplied in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store antibody at -20°C for up to one year.

Details zu CEBPA

Target: CEBPA (CCAAT/enhancer Binding Protein (C/EBP), alpha (CEBPA))

Andere Bezeichnung: C/EBP-alpha (CEBPA Produkte)

Synonyme: C/EBP-alpha antikoerper, CEBP antikoerper, C/ebpalpha antikoerper, CBF-A antikoerper, Cebp antikoerper, DBPCEP antikoerper, c/ebpa antikoerper, cb1062 antikoerper, wu:fj20f03 antikoerper, C/EBP antikoerper, C/EBPalpha antikoerper, xC/EBP antikoerper, cC/EBP antikoerper, C/EBP alpha antikoerper, CCAAT/enhancer binding protein alpha antikoerper, CCAAT/enhancer binding protein (C/EBP), alpha antikoerper, CCAAT/enhancer binding protein alpha L homeolog antikoerper, CEBPA antikoerper, Cebpa antikoerper, cebpa antikoerper, cebpa.L antikoerper

Hintergrund: The protein encoded by this intronless gene is a bZIP transcription factor which can bind as a homodimer to certain promoters and enhancers. It can also form heterodimers with the related proteins CEBP-beta and CEBP-gamma. The encoded protein has been shown to bind to the promoter and modulate the expression of the gene encoding leptin, a protein that plays an important role in body weight homeostasis. Also, the encoded protein can interact with CDK2 and CDK4, thereby inhibiting these kinases and causing growth arrest in cultured cells.

Molekulargewicht: 42 kDa

Gen-ID: 1050

NCBI Accession: NP_004355

UniProt: P49715

Pathways: Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation